April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
The Relationship between Corneal Biomechanical Properties, Endothelial Cell Count and Corneal Pachymetry in Healthy Subjects
Author Affiliations & Notes
  • Elena Zemova
    Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
    Ophthalmology, Tver State Medical Academy, Tver, Russian Federation
  • Berna Akova Budak
    Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
    Ophthalmology, Uludag University, Bursa, Turkey
  • Berthold Seitz
    Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
  • Nora Szentmary
    Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
  • Achim Langenbucher
    Ophthalmology,
    Experimental Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
  • Footnotes
    Commercial Relationships  Elena Zemova, None; Berna Akova Budak, None; Berthold Seitz, None; Nora Szentmary, None; Achim Langenbucher, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 6446. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Elena Zemova, Berna Akova Budak, Berthold Seitz, Nora Szentmary, Achim Langenbucher; The Relationship between Corneal Biomechanical Properties, Endothelial Cell Count and Corneal Pachymetry in Healthy Subjects. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6446.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To investigate whether there is a correlation between corneal biomechanical properties, endothelial cell count and corneal pachymetry in healthy subjects.

 
Methods:
 

This prospective study comprised 38 eyes of 38 subjects with normal corneas. All subjects underwent complete ocular examination including intraocular pressure, objective refraction, slitlamp biomicroscopy. Topographic measurements and corneal pachymetry were performed using Scheimpflug-based (Pentacam HR, Oculus, Germany) corneal topographer. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured with Ocular Response Analyzer (ORA Reichert Ophthalmic Instruments, Buffalo, NY). Endothelial cell count measurement was done using specular microscope (EM-3000, Tomey, Japan).

 
Results:
 

Thirty-eight eyes of 38 healthy subjects with a mean age of 29.6±9.4 years (range: 17-55 years) were included in the analysis. Mean corneal hysteresis was 11.3±1.8 mmHg and mean corneal resitance factor was 11.1±0.9 mmHg. The mean endothelial cell count was found to be 2689±212 cells/mm². No correlation was found between biomechanical properties of cornea and endothelial cell count (P>0.05; r=0.22). There was a significant correlation between CH, CRF and corneal thickness (P<0.0001; r =0.75).

 
Conclusions:
 

The corneal biomechanical properties correlated significantly with corneal thickness. Further studies are required to broaden the knowledge of relationship between corneal biomechanical properties, anterior segment topography and density of endothelial cells.

 
Keywords: cornea: clinical science • anterior segment • imaging/image analysis: clinical 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×