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Padmapriya Ramamoorthy, Jason J. Nichols; Compliance Factors Associated With Dry Eye In Soft Contact Lens Wearers. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6519.
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To determine if compliance factors are associated with contact lens related dry eye.
The data were derived from subject responses to a compliance survey in a cross sectional study of contact lens wearers with and without dry eye. Eligibility criteria for the study included soft contact lens wear for at least 1 year or more, ages 18 to 39 years, daily (non-overnight) lens wear and good systemic and ocular health. The Contact Lens Dry Eye Questionnaire (CLDEQ) score was used to determine dry eye status. The compliance survey included several questions on ease in contact lens care, rub and rinse practices, contact lens and lens case replacement frequency, solution replacement/ topping off and sleeping in contact lenses. Non parametric tests including the Mann Whitney test and Fisher’s exact test were performed as applicable for statistical analysis of the data.
The analysis included 24 asymptomatic lens wearers and 19 with contact lens related dry eye. Average age of all subjects was 26.4 ± 5.2 years and 59% were female. The following compliance factors were found to be significantly different between the asymptomatic and dry eye groups. For ease in lens care, the average for the non-dry eye group was 9.5 ± 0.9, while the average for the dry eye group was 8.1 ± 2.2 (p = 0.001). For lens rubbing on both surfaces of the contact lens, only 17% of the non-dry eye group reported compliance, while 47% of the dry eye group reported compliance (p = 0.046). A few other non-significant trends were observed. 74% were female in the dry eye group in comparison to 42% in the non-dry eye group (p = 0.063). For lens rubbing time, the mean values were 5.8 ± 8.3 in the dry eye group and 2.2 ± 4.1 in the non-dry eye group (p = 0.085). No differences were detected in age and other compliance factors such as contact lens case replacement frequency, care solution topping off, lens rinsing and, sleeping in lenses.
Although perceived ease in lens care was rated lower by the dry eye group, their lens rub compliance was significantly better than the non-dry eye group. While this needs to be verified with a larger sample, the findings also indicate that factors other than compliance could play a bigger role in contact lens related dry eye.
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