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Yuchen Huo, Scott S. Perry, Alexander Rudy, Alice Wang, Howard A. Ketelson, David L. Meadows; Composition and Friction Analysis of Copolymer Solution Treatments of Silicone Hydrogel Contact Lens Surfaces. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6530.
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The surface chemical compositions of three major brands of silicone hydrogel (SH) contact lenses were analyzed using X-ray photoelectron spectroscopy (XPS) prior to and following treatment in a test solution of diblock copolymer of polyethylene oxide and polybutylene oxide. Atomic force microscopy (AFM) was also employed to evaluate the surface topography and frictional properties of these lenses prior to and following similar solution treatments.
For surface compositional analysis with XPS, lens surfaces have been prepared through a vacuum drying procedure, in which the hydrogel is taken from a fully hydrated state directly to an ultraclean, ultrahigh vacuum environment. Contact and tapping mode AFM were used to measure the frictional and topographical properties in aqueous environments.
Prior to treatment, differences in surface elemental composition of the various lenses were found to reflect known bulk compositions and/or respective surface treatments. Following solution treatment, surface chemical modifications were apparent in balafilcon A (PureVision®) and lotrafilcon B (O2 OPTIX®), especially in the distribution chemical functionalities present at the surface. Only modest changes in surface composition were observed for the senofilcon A (ACUVUE® OASYS®) system. AFM measurements in saline revealed large disparities between the coefficients of friction of the three lenses, with balafilcon A and lotrafilcon B exhibiting coefficients of friction approximately five times greater than that of senofilcon A. Lens surface treatment with the diblock copolymer test solution produced a significant reduction in the coefficients of friction of the two lenses exhibiting higher friction, yet only a small reduction in friction was observed for senofilcon A lens.
Together, these results depict a strong correlation between the surface chemistry and frictional response of the lens systems as they relate to solution treatment with this specific diblock copolymer. This study indicated that diblock copolymers containing polyethylene oxide and polybutylene oxide may have a positive impact on the lubrication and wetting properties of silicone hydrogel lenses.
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