March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Postural Intraocular Pressure Changes After Trabeculectomy Over Time
Author Affiliations & Notes
  • Akira Sawada
    Ophthalmology, Gifu Univ Grad School of Med, Gifu-shi, Japan
  • Tetsuya Yamamoto
    Ophthalmology, Gifu Univ Grad School of Med, Gifu-shi, Japan
  • Footnotes
    Commercial Relationships  Akira Sawada, None; Tetsuya Yamamoto, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 5089. doi:
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    • Get Citation

      Akira Sawada, Tetsuya Yamamoto; Postural Intraocular Pressure Changes After Trabeculectomy Over Time. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5089.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To determine whether trabeculectomy affects the posture-induced changes in the intraocular pressure (IOP) and whether it is maintained for months.

Methods: : Twenty-nine eyes of 29 patients with open-angle glaucoma who were scheduled for their initial trabeculectomy with adjunctive mitomycin C were subjected. The IOP was measured in the sitting and the lateral decubitus position with an ICare rebound tonometer before, and 1, 3, and 12 months after the surgery.

Results: : The mean baseline IOP measured with the ICare was 17.4 ± 4.9 mmHg in the sitting position and 21.3 ± 5.6 mmHg in the lateral decubitus position (P<0.001). This postural IOP difference, +3.8 mmHg, was reduced to +1.3 ± 1.7 mmHg at one month and to +0.8 ± 1.5 mmHg at 3 months after the surgery (P<0.001 and P=0.004, respectively). This decrease in the degree of posture-dependent IOP change was maintained at +1.7 ± 2.2 mmHg at 1-year postoperatively (P<0.001). In 3 cases, the postural IOP changes returned to the baseline level, and all 3 had a failed bleb.

Conclusions: : Our results indicate that trabeculectomy not only reduces the IOP but also reduces the degree of posture-induced changes in the IOP. However, even after successful trabeculectomy, a significant difference in the IOP was present between the sitting and the lateral decubitus position.

Keywords: intraocular pressure • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • wound healing 

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