Abstract
Purpose: :
To document the incidence of outer retinal tubulation (ORT) and its Spectral-domain optical coherence tomography (SD-OCT) features in wet age-related macular degeneration (AMD).
Methods: :
Retrospective review of consecutive series of 247 eyes treated with intravitreal Ranibizumab for wet AMD. The prevalence, number, size and shape of ORT were determined with En-face imaging and its corresponding B-scans.
Results: :
ORT was identified in 15 of 247 eyes (6.07%) during 25 months period. Multiple round or oval hyporeflective spaces with hyper reflective double layered borders on the B-scans are typical SD-OCT features of ORT which measured 50 to 310 um high and 510 to 2650 um wide.
Conclusions: :
ORT is a highly under diagnosed situation and it should be ruled out in advanced wet AMD eyes to avoid unnecessary interventions.
Keywords: age-related macular degeneration • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • photoreceptors