March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Macular Thickness Measurements using SD-OCT in Myopic Patients
Fabrizio Giansanti; Carla Donati; Gianni Virgili; Giacomo Abbruzzese; Giulia Pieretti; Stefania Cappelli; Matteo Giuntoli; Ugo Menchini
Author Affiliations & Notes
  • Fabrizio Giansanti
    Eye Clinic, University of Florence, Florence, Italy
  • Carla Donati
    Eye Clinic, University of Florence, Florence, Italy
  • Gianni Virgili
    Eye Clinic, University of Florence, Florence, Italy
  • Giacomo Abbruzzese
    Eye Clinic, University of Florence, Florence, Italy
  • Giulia Pieretti
    Eye Clinic, University of Florence, Florence, Italy
  • Stefania Cappelli
    Eye Clinic, University of Florence, Florence, Italy
  • Matteo Giuntoli
    Eye Clinic, University of Florence, Florence, Italy
  • Ugo Menchini
    Eye Clinic, University of Florence, Florence, Italy
  • Footnotes
    Commercial Relationships  Fabrizio Giansanti, None; Carla Donati, None; Gianni Virgili, None; Giacomo Abbruzzese, None; Giulia Pieretti, None; Stefania Cappelli, None; Matteo Giuntoli, None; Ugo Menchini, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 5183. doi:
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      Fabrizio Giansanti, Carla Donati, Gianni Virgili, Giacomo Abbruzzese, Giulia Pieretti, Stefania Cappelli, Matteo Giuntoli, Ugo Menchini; Macular Thickness Measurements using SD-OCT in Myopic Patients. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5183.

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Abstract

Purpose: : To determine the repeatability of TopCon SD-OCT measures of retinal thickness in myopic patients with or without choroidal neovascularitazion (CNV).

Methods: : Twenty-four eyes of 23 consecutive patients with pathologic myopia without CNV and 24 eyes of 24 consecutive patients with pathologic myopia with CNV underwent an OCT imaging session to evaluate central foveal thickness (CFT). Three 3D (Macular Cube) and three Radial protocol scans sets were acquired by two experienced operator certified for clinical trials work. The intra-examiner repeatability and the inter-examiner reproducibility of retinal thickness measurements were calculated according to the methods outlined by Bland and Altman.

Results: : In myopic patients without CNV the limits of agreement (LA 95%) of intra- observer repeatibility were: +/- 37 micron with 3-D scan (automatic measure), +/- 66 micron with 3-D scan (manual measure), +/- 33 micron with radial scan (automatic measure), +/-51 with radial scan (automatic measure). The limits of agreement (LA 95%) of inter-observer reproducibility were: +/- 84 micron with 3-D scan (manual measure), +/-121 micron (automatic measure), +/- 93 micron with radial scan (manual measure), +/- 94 with radial scan (automatic measure).In myopic patients with CNV the limits of agreement (LA 95%) of inter-observer reproducibility were: +/- 120 micron with 3-D scan (automatic measure), +/- 51 micron with 3-D scan (manual measure), +/- 58 micron with radial scan (automatic measure), +/- 85 with radial scan (automatic measure). The limits of agreement (LA 95%) of inter-observer reproducibility were: +/- 114 micron with 3-D scan (manual measure), +/-289 micron (automatic measure), +/- 137 micron with radial scan (manual measure), +/- 276 with radial scan (automatic measure).

Conclusions: : The repeatibility and reproducibility of TopCon SD-OCT measures of retinal thickness in myopic patients with or without choroidal neovascularitazion (CNV) showed high variability.

Keywords: myopia • retina • macula/fovea 
© 2012, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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