March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
The Visual Acuity Model Of The Artificial Retina On The Basis Of The Cone Cell Distribution
Author Affiliations & Notes
  • Hum Chung
    Ophthalmology,
    Seoul National University, Seoul, Republic of Korea
  • Yong-Wan Lee
    Electrical Engineering, Pohang University of Science and Technology, Pohang, Republic of Korea
  • Jong-Mo Seo
    Ophthalmology,
    Electrical Engineering,
    Seoul National University, Seoul, Republic of Korea
  • Hee-Sun Park
    Ophthalmology,
    Seoul National University, Seoul, Republic of Korea
  • So-Hyun Bae
    Bioengineering,
    Seoul National University, Seoul, Republic of Korea
    Hallym University Hospital, Seoul, Republic of Korea
  • Bum-Joo Cho
    Ophthalmology,
    Seoul National University, Seoul, Republic of Korea
  • Tae-Wan Kim
    Ophthalmology,
    Seoul National University, Seoul, Republic of Korea
    Boramae Medical Center, Seoul, Republic of Korea
  • Hyeong-Gon Yu
    Ophthalmology,
    Seoul National University, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  Hum Chung, None; Yong-Wan Lee, None; Jong-Mo Seo, None; Hee-Sun Park, None; So-Hyun Bae, None; Bum-Joo Cho, None; Tae-Wan Kim, None; Hyeong-Gon Yu, None
  • Footnotes
    Support  Korea Health 21 R & D Project A050251 by MIHWAF, Technology Innovation Program 10033634 by MKE, Public Welfare and Safety Program 2010-0020847 by MEST
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 5546. doi:https://doi.org/
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      Hum Chung, Yong-Wan Lee, Jong-Mo Seo, Hee-Sun Park, So-Hyun Bae, Bum-Joo Cho, Tae-Wan Kim, Hyeong-Gon Yu; The Visual Acuity Model Of The Artificial Retina On The Basis Of The Cone Cell Distribution. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5546. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Visual acuity of the artificial retina was predicted on the basis of the cone cell distribution investigated by Curcio CA et al. (J Comp Neurol. 1990 Feb 22;292(4):497-523) Macula usually deteriorated severely in all retinal layers in the recepients, pericentral visual acuities were simulated.

Methods: : The visual acuity was modeled as minimum discernable and minimum separable. Receptive field was designed as cone cell and bipolar cell to be matched one by one, and honeycomb-shape arrangement of the bipolar cell to ganglion cell. Minimum discernable model was considered as a solitary activation of one photoreceptor, and minimum separable model as two activated photoreceptors intervened by one inactive photoreceptor. Pericentral visual acuities between the visual angles of five to fifteen degrees were considered as the visual acuity that can be achieved by the artificial retina.

Results: : Pericentral visual acuity was about 20/80 in minimum discernable model, and about 20/200 in minimum separable model. This model was validated in normal volunteers by the peripheral visual acuity measurement program developed by the authors.

Conclusions: : Artificial retina may give useful visual acuity in the blind for the daily lives with its optimized condition.

Keywords: retina • visual acuity • computational modeling 
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