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Chaohong Li, Hao Chen, Yiyu Li, zhihao Tang; Optics Design For Confocal Scanning Laser Ophthalmoscope. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5681.
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Adaptive optics scanning laser ophthalmoscope (AOSLO) is being used for non-invasive, in vivo and high-resolution imaging of the retina, most of the AOSLO suffered from large system aberration (which was mainly produced from sphere mirrors) and living eye’s defocus aberration (which was generally compensated by inserting trial lens at the eye pupil plane). An AOSLO system with cross-compensation optics design was presented here to estimate the system aberration, such as astigmatism and coma, and to help removing the blur of retina image.
Three pairs of sphere mirrors were used in our AOSLO system to expand and relay the beam of system, these sphere mirrors were designed to be placed on different layers with different central height instead of one layer, to cross-compensate the system aberration.
Optical diffraction-limit was obtained in the new AOSLO system without any additional trial lens, the strehl ratio of point spread function (PSF) of optics system is improved from 0.16 to 0.86 within 2.5X2.5 °field of view (FOV) angle at 6 mm eye pupil, which make AOSLO system more compact, simple and easy for operating in clinical applications.
Estimating the system aberration by optical design optimization is very critical for the retina imaging system, it will help improving the imaging quality and decreasing the cost of adaptive optics system. On the other hand, designing the system in different optical layers will make the optical system more compact and easy for clinical application.
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