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Alexander Kyhnel, III, Sindri Traustason, Javad Nouri Hajari, Jens Folke Kiilgaard, Einar Stefánsson, Morten La cour; The Effect Of Retinal Detachment On Retinal Oxygenation. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5798.
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In retinal detachment the supply of oxygen to the retina from the choroid is diminished.Little is known on the effects of retinal detachment on oxygen extraction in retinal vessels.We therefore studied the arterio-venous oxygen saturation difference in the temporal retinal vessels in patients with rhegmatogenous retinal detachment.
Patients with macula-on rhegmatogenous retinal detachment in one eye and a healthy fellow eye were evaluated for macular involvement with OCT upon admission. We included eyes with a detachment involving only the superior or inferior temporal quadrant, i.e. detachments that respected the horizontal meridian. We excluded cases where it was not possible to evaluate the temporal vessels in an area with fully attached retina.Six cases fulfilled the in- and exclusion criteria (all male, mean age: 64±9 years). Patients underwent oximetry measurements with Oxymap Retinal Oximeter (ORO), version T1.The ORO registers retinal vessels automatically on fundus images and returns the proportion of oxygen bound haemoglobin as a percentage.
The arterio-venous O2 saturation difference was significantly lower in the affected vascular arcade (mean saturation difference: 22±9 %) compared to the healthy vessel arcade in the affected eye (Mean 33±5 %, p=0.012) as well as the mean of both temporal arcades in the fellow eye (Mean 36±3 %, p= 0.013).
Our preliminary results show that oxygen extraction from retinal vessels is affected by retinal detachment. The oxygen extraction was found to be lower in the affected region than in regions with no detachment, indicating decreased metabolic activity in the affected area.
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