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Ping Hou, Xiaoting Mai, Jianlong Zheng, Haoyu Chen, Weiqi Chen; Investigation Of Subretinal Fibrosis In Rhegmatous Retinal Detachment With Spectral Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5803. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To invesigate the tomographic characters, risk factors and functional effect of subretinal fibrosis in rhegmatous detachment.
A retrospective study was performed. Patients with rhegmatous retinal detachment at Joint Shantou International Eye Center were recruited. The clinical data collected included gender, age, disease course, axial length, preoperative intraocular pressure, preoperative best corrected visual acuity (BCVA) and postoperative BCVA. Spectral domain optical coherence tomography (SD-OCT) were reviewed. The height of foveal detachment was measured and subretinal fibrosis identified. Chi square test and Mann-Whitney U test were used to compared the characters between patients with and without subretinal fibrosis.
Totally 177 eyes of 177 patients with rhegmatous retinal detachment were examined. Subretinal fibrosis was indentified in 18 eyes. The tomographic characters were hyperreflective lesion at subretinal space. The patients with subretinal fibrosis were younger, (24.3 vs 49.2 years, p<0.001), had longer course (314.4 vs 42.3 days, p<0.001), higher intraocular pressure (13.3 vs 10.6 mmHg, p<0.001), and lower foveal detachment (313.1 vs 524.6 um, p<0.001). There were no statistical differences in gender, axial length, peroperative or postoperative BCVA between the two groups of patients with or without rhegmatous retinal detachment.
Subretinal fibrosis was showed as hyperreflective lesion on spectral domain optical coherence tomography. Younger age, lower foveal detachment and higher intraocular pressure were the risk factors of subretinal fibrosis, which did not affect the preoperative or postoperative visual acuity.
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