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Elsbeth J. Van Zeeburg, Boy Braaf, Matteo G. Cereda, Jan C. van Meurs, Johannes F. de Boer; Correlation Of The Detection Of Blood Flow In An RPE-choroid Graft With Phase-resolved Doppler OFDI, With The Revascularization Steps Found On SD-OCT. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5845.
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© ARVO (1962-2015); The Authors (2016-present)
To correlate the detection of blood flow in a retinal pigment epithelium (RPE) choroid graft with phase-resolved Doppler Optical Frequency Domain Imaging (Doppler-OFDI) and the revascularization steps found on commercially available Spectral Domain Optical Coherence Tomography (SD-OCT).
Five patients with age related macular degeneration underwent an RPE choroid graft translocation. Pre- and postoperative SD-OCT scans were made, in which the thickness of the graft, number and diameter of the vessels, and thickness of the fluid under the graft were measured; in order to monitor the revascularization process of the graft. Additionally phase-resolved Doppler-OFDI (Swept-Source OCT) scans were made to directly detect the presence of flow.
SD-OCT was able to detect both the afferent and efferent vessel in growth phase in 5 out of 5 patients.Doppler-OFDI detected flow in 4 patients when SD-OCT showed the efferent vessel in growth phase. In one patient Doppler-OFDI detected flow one visit later than SD-OCT showed the efferent vessel in growth phase.
Doppler-OFDI was able to confirm blood flow in a free RPE choroid graft and correlated well with the establishment of revascularization as suggested on SD-OCT.
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