March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
A Mechanics Based Model Of A Detaching Retina
Author Affiliations & Notes
  • Howard F. Fine
    Ophthalmology, Robert Wood Johnson Univ Hosp, New Brunswick, New Jersey
  • Jonathan L. Prenner
    Ophthalmology, Robert Wood Johnson Univ Hosp, New Brunswick, New Jersey
  • Peter L. Bishay
    Mechanical and Aerospace Engineering, Rutgers University, Piscataway, New Jersey
  • Daniel B. Roth
    Ophthalmology, Robert Wood Johnson Univ Hosp, New Brunswick, New Jersey
  • William J. Bottega
    Mechanical and Aerospace Engineering, Rutgers University, Piscataway, New Jersey
  • Footnotes
    Commercial Relationships  Howard F. Fine, Allergan Inc (C), Genentech Inc (C), Ophthotech Inc (C); Jonathan L. Prenner, Neovista Inc (I), Ophthotech Inc (I); Peter L. Bishay, None; Daniel B. Roth, Allergan Inc. (C), Genentech Inc. (C), QLT (C), Regeneron Inc. (C); William J. Bottega, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 6362. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Howard F. Fine, Jonathan L. Prenner, Peter L. Bishay, Daniel B. Roth, William J. Bottega; A Mechanics Based Model Of A Detaching Retina. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6362.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To advance the current technical view of retinal detachment and develop a rigorous mechanics based model of the process.

 
Methods:
 

The mathematical model (Fig. 1a) incorporates elements of structural and detachment mechanics (spherical shell theory and Griffith type detachment criterion) in an energy formulation. The calculus of variations is employed, with the propagating boundary of the detached region of the retina allowed to vary as well as the displacements. This yields the self-consistent energy release per unit detached area of retina as the "driver" of the detachment process, and formulae for critical stress and critical radial deflection that provide a basis for measuring critical parameters (Fig.1b).

 
Results:
 

Results are presented in the form of threshold curves for the detaching structure, and reveal characteristic behavior, including threshold levels and stability for detachment, and the influence of the presence and size of a retinal tear on detachment propagation. The model predicts that once detachment ensues it does so in an unstable manner and is extensive in scope. Results also suggest that, under appropriate conditions, the presence and size of a retinal tear or hole can have a stabilizing effect with regard to detachment propagation. "Dimpling" of the retina is predicted for detachment angles ≥ 0.3 radians. The influence of altering material parameters such as fibril stiffness, Poisson's ratio (between 0.1 and 0.49), and thickness ratio, as well as the tear size are presented. The latter shows that, under appropriate circumstances, the presence and size of a retinal tear can have a stabilizing effect on detachment propagation.

 
Conclusions:
 

A mathematical model to describe the mechanics of a detaching retina was devised incorporating an energy based criterion for detachment propagation. The model describes under what conditions a detachment will progress, predicts "dimpling" phenomenon of the retina under specific circumstances, and indicates that once propagation ensues it will be extensive.  

 
Keywords: retinal detachment • anatomy • motion-3D 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×