March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Posterior Capsule Opacification of a 1-piece and a 3-piece Microincision Intraocular Lens - 1 year Comparison
Author Affiliations & Notes
  • Ana Prinz
    Department of Ophthalmology, Hietzing Hospital, Vienna, Austria
  • Birgit Weingessel
    Department of Ophthalmology, Hietzing Hospital, Vienna, Austria
  • Oliver Findl
    Department of Ophthalmology, Hanusch Hospital, Vienna, Austria
  • Pia V. Vecsei-Marlovits
    Department of Ophthalmology, Hietzing Hospital, Vienna, Austria
  • Footnotes
    Commercial Relationships  Ana Prinz, None; Birgit Weingessel, None; Oliver Findl, None; Pia V. Vecsei-Marlovits, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 6623. doi:
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      Ana Prinz, Birgit Weingessel, Oliver Findl, Pia V. Vecsei-Marlovits; Posterior Capsule Opacification of a 1-piece and a 3-piece Microincision Intraocular Lens - 1 year Comparison. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6623.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : The aim of this study was to compare the intensity of posterior capsular opacification (PCO) between the 1-piece and 3-piece haptic designs of the hydrophobic microincision intraocular lens (MICS IOL) 1 year after cataract surgery.

Methods: : This randomized, prospective, patient and examiner masked clinical trial comprised 80 eyes of 40 patients with age-related cataract. Each patient underwent cataract surgery in both eyes and received a 1-piece MICS IOL (Hoya AF-1iMics NY-60, Hoya, Japan) in one eye and a 3-piece MICS IOL (Hoya AF-1iMics Y-60H, Hoya, Japan) in the other eye. At year 1 follow-up, the patients were examined at the slit lamp, visual acuity (VA) was determined and standardized high-resolution digital retroillumination images were taken for objective quantification of regeneratory PCO. The intensity of fibrotic PCO was assessed subjectively at the slit-lamp (scale 0-3) and the amount of regeneratory PCO (score range 0-10) was assessed objectively using automated image analysis software (AQUA).

Results: : There was no significant difference between IOL styles in best-corrected VA, rhexis/IOL overlap, decentration of the IOL and amount of fibrotic PCO. Capsular folds occurred significantly more often in the 3-piece IOL group (1-piece, 9 cases, 3-piece, 18 cases; P = 0.01). The mean regeneratory PCO score was 0.3 in both IOL groups (P = 0.6). The Nd:YAG laser capsulotomy rate was slightly higher in the 3-piece group (2 cases vs. 1 at 1 year; P = 0.2).

Conclusions: : Modification of the MICS IOL from a 3-piece to a 1-piece open-loop haptic design caused no significant change in PCO amount and neodymium:yttrium-aluminium-garnet laser treatment rate. Compared with the 3-piece IOL, the 1-piece IOL led to significantly less capsular folds one year after surgery.

Clinical Trial: :, EK-09-227-0110

Keywords: posterior capsular opacification (PCO) • intraocular lens • cataract 

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