March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Prophylactic use of Intracameral Vancomycin in Cataract Surgery: a Retrospective Review of one Surgeon’s Experience Supporting its Safety and Efficacy
Author Affiliations & Notes
  • David M. Skale
    Ophthalmology, Loma Linda University, Loma Linda, California
  • Tomas A. Lopez
    Ophthalmology, Loma Linda University, Loma Linda, California
  • Michael E. Rauser
    Ophthalmology, Loma Linda University, Loma Linda, California
  • Carlo Manalo
    Ophthalmology, Loma Linda University, Loma Linda, California
  • Elliot Yoo
    Ophthalmology, Loma Linda University, Loma Linda, California
  • Footnotes
    Commercial Relationships  David M. Skale, None; Tomas A. Lopez, None; Michael E. Rauser, None; Carlo Manalo, None; Elliot Yoo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 6702. doi:
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      David M. Skale, Tomas A. Lopez, Michael E. Rauser, Carlo Manalo, Elliot Yoo; Prophylactic use of Intracameral Vancomycin in Cataract Surgery: a Retrospective Review of one Surgeon’s Experience Supporting its Safety and Efficacy. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6702.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To report on the incidence of endophthalmitis after cataract extraction when using intracameral vancomycin, and to report any suspected complications associated with its use.

Methods: : This is a retrospective chart review of all patients undergoing cataract surgery by one experienced staff surgeon at Loma Linda University between 2007 and 2011. All patients had received a fixed concentration of vancomycin (2mg/ml) given as a bolus injection into the anterior chamber at the end of the case. Pre-operative, operative, and post-operative data (one day, one week, and one month) was reviewed.

Results: : After review of 2437 cataract extractions, no cases of endophthalmitis were found. No complications attributable to intracameral vancomycin use were encountered.

Conclusions: : The review of patients gives further evidence to support the safety and efficacy of intracameral vancomycin in patients undergoing cataract surgery. Multi-center randomized controlled trials evaluating the use of post-operative bolus injection of intracameral vancomycin in cataract surgery are warranted.

Keywords: antibiotics/antifungals/antiparasitics • endophthalmitis • drug toxicity/drug effects 
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