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David M. Skale, Tomas A. Lopez, Michael E. Rauser, Carlo Manalo, Elliot Yoo; Prophylactic use of Intracameral Vancomycin in Cataract Surgery: a Retrospective Review of one Surgeon’s Experience Supporting its Safety and Efficacy. Invest. Ophthalmol. Vis. Sci. 2012;53(14):6702.
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To report on the incidence of endophthalmitis after cataract extraction when using intracameral vancomycin, and to report any suspected complications associated with its use.
This is a retrospective chart review of all patients undergoing cataract surgery by one experienced staff surgeon at Loma Linda University between 2007 and 2011. All patients had received a fixed concentration of vancomycin (2mg/ml) given as a bolus injection into the anterior chamber at the end of the case. Pre-operative, operative, and post-operative data (one day, one week, and one month) was reviewed.
After review of 2437 cataract extractions, no cases of endophthalmitis were found. No complications attributable to intracameral vancomycin use were encountered.
The review of patients gives further evidence to support the safety and efficacy of intracameral vancomycin in patients undergoing cataract surgery. Multi-center randomized controlled trials evaluating the use of post-operative bolus injection of intracameral vancomycin in cataract surgery are warranted.
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