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Chen Wei Pan, Tien Yin Wong, Xiao Yu Lin, Dharani Ramamurthy, Lan Chang, Raghavan Lavanya, Ren Yi Wu, Ying Feng Zheng, Tin Aung, Seang Mei Saw; Ocular Biometry in an Urban Indian Population: the Singapore Indian Eye Study. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2491.
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© ARVO (1962-2015); The Authors (2016-present)
To explore the distribution and determinants of ocular biometric parameters in Singaporean Indian adults.
A population-based, cross-sectional study was conducted on the Singaporean Indians aged 40 to 83 years. An age-stratified (10-year age group) random sampling procedure was performed to select participants. Ocular components including axial length (AL), anterior chamber depth (ACD) and corneal radius (CR) were measured by partial laser interferometry (IOL Master, Zeiss). Refraction was measured as the spherical equivalent (SE).
Of the 4,497 persons eligible to participate, 3,400 (response rate 75.6%) were examined. After excluding 502 individuals with previous cataract surgery, ocular biometric data on 2,785 adults were available. The mean AL for the whole population was 23.45 mm (95% confidence interval [CI] 22.25, 23.65). The mean AL was 23.53 mm, 23.49 mm, 23.35 mm and 23.25 mm in 40-49 years, 50-59 years, 60-69 years and 70-83 years age groups, respectively (P for trend<0.001). Men had significantly longer mean AL than women (23.68 mm versus 23.23 mm, P<0.001). In multivariate liner regression models, the AL was found to be longer in adults who were taller (P <0.001), heavier (P <0.001), more educated (P =0.004 for polytechnic; P =0.003 for university) and spent more time on reading (P =0.xxx). Increasing CR was associated with older age (P<0.001), increasing height (P<0.001), more time spent on computer usage (P<0.001) and the presence of cataract (P<0.001).
The mean AL of the Singaporean Indians is similar to that of the Singaporean Malays. Time spent on reading, height and educational level were the most consistent predictors of AL in Singaporean Indians.
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