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Akira Sugano, Yusuke Tanabe, Koko Saito, Kei Homma, Ryo Kawasaki, Takeo Kato, Takamasa Kayama, Hidetoshi Yamashita; Distribution And Association of Axial Length and Ocular Biometory in an Adult Japanese Population: The Funagata Study. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2498.
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© ARVO (1962-2015); The Authors (2016-present)
To describe a distribution and range of axial length and determine its risk associations with ocular and systemic parameters in an adult Japanese population sample, the Funagata Study.
The Funagata study is a population based epidemiologic study of Japanese aged 35+ years. Axial length, cornea thickness were obtained using a partial coherence laser interferometry (OA-1000, TOMEY cooperation, Nagoya, Japan). Corneal curvature (K) and refractive power were measured by an auto refracotmeter and keratometer (TONOREF II, NIDEK, Aichi, Japan). The spherical equivalent refraction (SER) was calculated by summering the spherical plus half the cylindrical refraction.
A geographically sampled 453 participants (229 women [50.5%]) were included for this analysis. Mean (±standar deviation) axial length, SER and K were 23.58±1.39mm, -0.89±3.04diopter (D) and 43.72±1.47D, respectively. Axial length and SER was deviated from normal distribution (Kolmogorov-Smimonv test p<0.01). In whole this study population, 95% and 99% range of axial length were 21.64 to 27.24mm and 21.20 to 29.90mm, respectively. Women had shorter axial length, larger K and thinner corneal thickness, but there were no difference between gender in SER. The axial length were negatively correlated with SER, K and age, and positively correlated with cornea thickness, intraocular pressure, best corrected visual acuity, body height and body weight. In multivariable adjusted model, body height (+0.05mm per 1cm in body height, 95%CI 0.04 to 0.06, p<0.01) and age (-0.014mm per 1 year of age, 95%CI -0.026 to -0.003, P<0.01) were independently associated with axial length.
Upper 95% range of axial length were 27.24 mm, which indicates a normal upper limit for axial length in adult population. Body height and age were independently associated with axial length.
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