April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Distribution And Association of Axial Length and Ocular Biometory in an Adult Japanese Population: The Funagata Study
Author Affiliations & Notes
  • Akira Sugano
    Ophthalmology,
    Yamagata University Sch of Med, Yamagata, Japan
  • Yusuke Tanabe
    Ophthalmology,
    Yamagata University Sch of Med, Yamagata, Japan
  • Koko Saito
    Ophthalmology,
    Yamagata University Sch of Med, Yamagata, Japan
  • Kei Homma
    Ophthalmology,
    Yamagata University Sch of Med, Yamagata, Japan
  • Ryo Kawasaki
    Ophthalmology,
    Yamagata University Sch of Med, Yamagata, Japan
    Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Australia
  • Takeo Kato
    Department of Neurology, Hematology, Metabolism,
    Yamagata University Sch of Med, Yamagata, Japan
    Global COE Program for Medical Sciences, Japan Society for the Promotion of Science, Yamagata, Japan
  • Takamasa Kayama
    Global COE Program for Medical Sciences, Japan Society for the Promotion of Science, Yamagata, Japan
  • Hidetoshi Yamashita
    Ophthalmology,
    Yamagata University Sch of Med, Yamagata, Japan
    Global COE Program for Medical Sciences, Japan Society for the Promotion of Science, Yamagata, Japan
  • Footnotes
    Commercial Relationships  Akira Sugano, None; Yusuke Tanabe, None; Koko Saito, None; Kei Homma, None; Ryo Kawasaki, None; Takeo Kato, None; Takamasa Kayama, None; Hidetoshi Yamashita, None
  • Footnotes
    Support  Global COE program of the Japan Society for the Promotion of Science
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 2498. doi:
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      Akira Sugano, Yusuke Tanabe, Koko Saito, Kei Homma, Ryo Kawasaki, Takeo Kato, Takamasa Kayama, Hidetoshi Yamashita; Distribution And Association of Axial Length and Ocular Biometory in an Adult Japanese Population: The Funagata Study. Invest. Ophthalmol. Vis. Sci. 2011;52(14):2498.

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Abstract

Purpose: : To describe a distribution and range of axial length and determine its risk associations with ocular and systemic parameters in an adult Japanese population sample, the Funagata Study.

Methods: : The Funagata study is a population based epidemiologic study of Japanese aged 35+ years. Axial length, cornea thickness were obtained using a partial coherence laser interferometry (OA-1000, TOMEY cooperation, Nagoya, Japan). Corneal curvature (K) and refractive power were measured by an auto refracotmeter and keratometer (TONOREF II, NIDEK, Aichi, Japan). The spherical equivalent refraction (SER) was calculated by summering the spherical plus half the cylindrical refraction.

Results: : A geographically sampled 453 participants (229 women [50.5%]) were included for this analysis. Mean (±standar deviation) axial length, SER and K were 23.58±1.39mm, -0.89±3.04diopter (D) and 43.72±1.47D, respectively. Axial length and SER was deviated from normal distribution (Kolmogorov-Smimonv test p<0.01). In whole this study population, 95% and 99% range of axial length were 21.64 to 27.24mm and 21.20 to 29.90mm, respectively. Women had shorter axial length, larger K and thinner corneal thickness, but there were no difference between gender in SER. The axial length were negatively correlated with SER, K and age, and positively correlated with cornea thickness, intraocular pressure, best corrected visual acuity, body height and body weight. In multivariable adjusted model, body height (+0.05mm per 1cm in body height, 95%CI 0.04 to 0.06, p<0.01) and age (-0.014mm per 1 year of age, 95%CI -0.026 to -0.003, P<0.01) were independently associated with axial length.

Conclusions: : Upper 95% range of axial length were 27.24 mm, which indicates a normal upper limit for axial length in adult population. Body height and age were independently associated with axial length.

Keywords: myopia • refraction 
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