April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Feature Analysis of Spectral-Domain Optical Coherence Tomography in Central Serous Chorioretinopathy
Author Affiliations & Notes
  • Ahsen Hussain
    St Paul's Eye Unit, Royal Liverpool Hospital NHS Trust, Liverpool, United Kingdom
  • James Hare
    Eye and Vision Sciences, University of Liverpool, Liverpool, United Kingdom
  • Alexandros Stangos
    St Paul's Eye Unit, Royal Liverpool Hospital NHS Trust, Liverpool, United Kingdom
  • Yalin Zheng
    Eye and Vision Sciences, University of Liverpool, Liverpool, United Kingdom
  • Jayashree Sahni
    St Paul's Eye Unit, Royal Liverpool Hospital NHS Trust, Liverpool, United Kingdom
  • Footnotes
    Commercial Relationships  Ahsen Hussain, None; James Hare, None; Alexandros Stangos, None; Yalin Zheng, None; Jayashree Sahni, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 3686. doi:https://doi.org/
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      Ahsen Hussain, James Hare, Alexandros Stangos, Yalin Zheng, Jayashree Sahni; Feature Analysis of Spectral-Domain Optical Coherence Tomography in Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3686. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To qualitatively and quantitatively analyse Spectralis OpticalCoherence Tomography (OCT) features in patients with treatment-naïveCentral Serous Chorioretinopathy (CSCR) and correlate morphometricfindings with vision and duration of symptoms.

 
Methods:
 

Prospective, observational study. Data was collected for LogMARvisual acuity and duration of symptoms (<3 months= acute;>3 months=chronic).OCT scans passing through the fovea wereanalysed for presence or absence of:• subretinal fluid(SRF)• intraretinal fluid (IRF)• pigment epithelialdetachment (PED)• irregularities of the inner boundaryof SRF• reflective irregularities of the photoreceptorinner/outer segment layer.• integrity of the external limitingmembrane (ELM)• central foveal thickness (CFT) includingSRF• SRF cross-sectional area• photoreceptor heightRetinallayers, cross-sectional area of fluid and foveal height weremarked using ImageJ 1.43 (NIH, Maryland, USA). and analysedby our proprietary software to calculate the thickness of eachretinal layer at the fovea.

 
Results:
 

Data was collected from 26 eyes of 25 patients. Two eyes wereasymptomatic; 11 had acute symptoms, 12 had chronic symptoms.Data for one patient was unavailable.See Results Table Images1&2

 
Conclusions:
 

Feature analysis of Spectralis OCT images has identified severalhallmark microstructural abnormalities in patients with CSCR.However, morphometric changes on OCT did not appear to correlatewith clinical presentation in CSCR.  

 

 
Keywords: retina • imaging/image analysis: clinical • chorioretinitis 
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