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Chetan Soni, Dean Hainsworth; Spectral Domain Optical Coherence Tomography in Asteroid Hyalosis: A Prospective Study. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3695.
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© ARVO (1962-2015); The Authors (2016-present)
To examine the role of spectral domain optical coherence tomography (OCT) in asteroid hyalosis (AH)
We conducted a prospective, observational case series. Consecutive subjects with AH were enrolled during study period. They underwent fundus photography and spectral domain OCT. A blinded observer graded fundus photographs using our grading system for AH. These were then compared with the signal strength on macular cube function of spectral domain OCT. Primary outcome measure was the ability to identify retinal layers using spectral domain OCT for different grades of AH. Secondary outcome measure was to compare the grading system to signal strength of macular cube function using spectral domain OCT.
Sixteen eyes from fourteen subjects with AH were evaluated. On an average, the signal strength for AH grade I was 9.5/10, AH grade II was 5.5/10, AH grade III was 4.5/10 and Ah grade IV was 3.5/10. Using correlation of coefficient function, a strong negative correlation was identified between the grading scale and signal strength (r value: -0.836). Spectral domain OCT provided adequate information on vitreo-retinal interface, inner and outer retinal layers across all grades of AH.
There is a strong negative correlation between our AH grading system and signal strength on spectral domain OCT. Spectral domain OCT provides valuable information on retinal architecture in patients with AH, even at low signal strengths.
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