April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Anatomic And Functional Features Of Ischemic Diabetic Maculopathy
Author Affiliations & Notes
  • Elisabetta Chiariello Vecchio
    Oftalmologia, Universita Federico II, Napoli, Italy
  • Gilda Cennamo
    Oftalmologia, Universita Federico II, Napoli, Italy
  • Giuseppe de Crecchio
    Oftalmologia, Universita Federico II, Napoli, Italy
  • Giovanni Cennamo
    Oftalmologia, Universita Federico II, Napoli, Italy
  • Footnotes
    Commercial Relationships  Elisabetta Chiariello Vecchio, None; Gilda Cennamo, None; Giuseppe de Crecchio, None; Giovanni Cennamo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 3701. doi:
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      Elisabetta Chiariello Vecchio, Gilda Cennamo, Giuseppe de Crecchio, Giovanni Cennamo; Anatomic And Functional Features Of Ischemic Diabetic Maculopathy. Invest. Ophthalmol. Vis. Sci. 2011;52(14):3701.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To describe anatomic and functional features of ischemic diabetic maculopathy by high-speed Fourier-domain optical coherence tomography (FD-OCT) and Fundus Microperimetry

Methods: : In a prospective study, fortyfive consecutive patients ( 70 eyes) with ischemic diabetic maculopathy underwent best corrected visual acuity determination, fluorescein angiography, Fundus Microperimetry( MP1, Nidek Inc, Italy) and RTVue FD-OCT. Main outcome measures were fixation stability and position and mean retinal sensitivities within the 4 central degrees areas. Foveal thickness and Ganglion cell complex (GCC) thickness were measured by RTVue FD-OCT.

Results: : Fixation was central in 46 eyes ( 65,71% ) and poor in 4 eyes ( 5,71% ), and predominantly eccentric in 10 eyes ( 14,28%). Stable in 40 ( 57,14% ) and relative unstable in 16 ( 22,85% ) and unstable in 4 eyes ( 5,71% ). Mean central 4 degrees retinal sensitivity- SD was 8.5 ±2.5.; LogMAR BCVA ranged from 0.1 to 1.3. Mean OCT foveal thickness -SD was 120 ±30.83.GCC thickness average was 75.2.

Conclusions: : FD-OCT showed a reduction of GCC thickness in all eyes with ischemic diabetic maculopathy. Whereas stability of fixation and foveal thickness play a major role in conditioning BCVA.

Keywords: ganglion cells • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • macula/fovea 

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