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Tanuj Dada, Neha Chaturvedi, Tushar Agarwal, Anita Panda, Praveen Vashisht, GVS Murthy; Evaluation Of Compliance To Topical Therapy In POAG and PACG Patients in India. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5034.
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To evaluate the compliance to topical ocular hypotensive medications in patients of primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) in the Indian population.
A cross sectional study of 600 patients of POAG and PACG recruited from out patient services of a university hospital was performed using a semi structured questionnaire. Patients on bilateral therapy for a duration between 6 months to 3 years were included. Non-Compliance being defined as missing of 1 or more doses in the past one month. Factors leading to non-compliance were classified into four categories- situational, provider, regimen and system related.
Out of the 600 patients (300 POAG and 300 PACG) interviewed, 340(56.7%) were males, 260(43.3%) females. The mean age of patients was 60.2 + 11.6 years . Three hundred and sixty patients (60%) were found to be non-compliant, including 160 with POAG and 200 with PACG (p = 0.01). Fifty patients (14%) reported on missing medication for more than one week . The factors leading to non-compliance were - Situational (510 patients,85%), Regimen related (60 patients,10%), Provider related (18 patients,3%), System related (12 patients,2%). The three most common situational obstacles to compliance were forgetfulness (45%), travel (35%) and unable to purchase drug due to lack of money (15%). Two hundred and forty patients (43.3%) were financially dependent on a care taker for their medications . Out of the 290 literate patients 170 (58.6%) were compliant while out of the 310 illiterate patients, only 60 patients (19.34%) were complaint [p = 0.001 ].
High rates of non-compliance were seen in the Indian population with 6 out of 10 patients missing medications . The non compliance rates were higher in PACG as compared to POAG patients and in illliterate versus literate patients. Situational factors were implicated as the cause for non-compliance in majority of the patients.
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