April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Specificity Of HRT MRA And GPS Within The Bridlington Eye Assessment Project
Author Affiliations & Notes
  • Ali Poostchi
    Department of Ophthalmology, Nottingham University Hospitals, Nottingham, United Kingdom
  • Haogang Zhu
    Optometry and Visual Science, City University, London, United Kingdom
  • David P. Crabb
    Optometry and Visual Science, City University London, London, United Kingdom
  • Stephen A. Vernon
    Ophthalmology, Nottingham Univ Queens Med Ctr, Nottingham, United Kingdom
  • Footnotes
    Commercial Relationships  Ali Poostchi, None; Haogang Zhu, None; David P. Crabb, None; Stephen A. Vernon, None
  • Footnotes
    Support  Unrestricted grant from Guide Dogs for the Blind
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5045. doi:
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      Ali Poostchi, Haogang Zhu, David P. Crabb, Stephen A. Vernon; Specificity Of HRT MRA And GPS Within The Bridlington Eye Assessment Project. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5045.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To determine the specificity of the Heidelberg Retina Tomography automated shape analysis tool (ASAT) in a normal elderly population.

Methods: : 6540 eyes of 3470 normal subjects (defined with fields and IOP) with a mean age 74 years, range 63 -99 years, from The Bridlington Eye Assessment Project (BEAP) were selected. Patients underwent optic nerve imaging using HRT 2 as well as a standard ophthalmic examination by trained optometrists. Scan data was imported into HRT3 for calculation of Moorfields Regression Analysis 3 (MRA3) and Glaucoma Probability Score (GPS), the internal ASAT. Subjects with a HRT mean pixel height standard deviation of greater than 68 um were excluded from the analysis.

Results: : When borderline cases were classified as abnormal, the specificities of GPS, Moorfields Regression Analysis 3 (MRA 3) and Clinical evaluation were 77 %, 83% and 94% respectively. This rose to 83% and 92 % for GPS and MRA when borderline cases were re-classified as normal.

Conclusions: : When used in isolation, GPS is less specific than MRA3 or fundoscopy by trained optometrists when screening a population of normal elderly individuals.

Keywords: imaging/image analysis: clinical • optic nerve 

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