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Na Hee Kang, Kyu-Ryong Choi, Namil Study Group; Small, Myopic Optic Disc and Normal Tension Glucoma in South Korea: The Namil Study. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5050.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the prevalence of glaucoma and peripapillary atrophy with clinical features according to the optic disc size and to evaluate the prevalence of glaucoma according to the presence of peripapillary atrophy in Namil-myon area in central south Korea.
Of 1532 participants in Namil study, 2804 eyes in 1420 subjects with available fundus photographs were included in this study. After the estimation of optic disc size on the photographs using the Image J software, participants were classified into the 3 groups(small, medium and large optic disc group). We compared the clinical features, the prevalence of peripapillary atrophy and glaucoma among the three groups. And we evaluated the prevalence of glaucoma according to the presence of peripapillary atrophy.
The mean age(62.0±11.7 years) in small disc group was younger than other groups. And people with smaller optic disc have a deeper anterior chamber, longer axial length and more myopic spherical equivalent (-0.1±2.5 diopter). The peripapillary atrophy and zone beta atrophy were detected more frequently in large optic disc group(29.7%, p<0.01, 17.3%, p<0.01, respectively). The prevalence of glaucoma was 3.0% in total. In small disc group, the prevalence of glaucoma was higher than other groups(p=0.31) and the normal tension glaucoma was statistically significantly more frequent in this group (p=0.03). The prevalence of normal tension glaucoma was higher in the subjects with zone beta peripapillary atrophy(6.0% Vs. 3.0%, p<0.01).
The optic disc size were related to the age, spherical equivalent, axial length and anterior chamber depth in residents of Namil-myon area. The zone beta peripapillary atrophy occurs more frequently in large optic disc group. The glaucoma was detected more frequently in small disc group and especially, the prevalence of normal tension glaucoma was significantly higher in this group. The prevalence of glaucoma was higher in the people with zone beta atrophy. Therefore, we have to consider the clinical features when evaluate the optic disc size. And we must carefully investigate the presence of normal tension glaucoma in the patients with small optic disc or zone beta atrophy.
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