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Hiroki Nomoto, Chota Matsumoto, Sachiko Okuyama, Sonoko TAkada, Shigeki Hashimoto, Eiko Arimura, Fumi Tanabe, Tomoyasu Kayasawa, Mariko Eura, Yoshikazu Simomura; Relationships Between NFLT Analyzed By Normal Database With Cirrus OCT And Visual Field Testing Results. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5075.
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© ARVO (1962-2015); The Authors (2016-present)
NFLT results of Cirrus OCT is analyzed by built-in normal database and classified into 3 grades (normal, 5 percentile(%tile) limit and 1%tile limit). This instrument can measure total average NFLT, quadrant NFLT and 12 clock-hour NFLT. Our interest is that NFLT classification of cirrus OCT has how much detecting ability with glaucoma.
Subjects were 103 eyes of 103 glaucoma patients and 45 eyes of 45 glaucoma suspects. Glaucoma patients were divided into early, moderate and advanced stages by mean deviation (MD) of SAP result. All subjects underwent SAP, FDT, Flicker perimetry, SWAP and cirrus OCT. Visual field testing results were evaluated by the number of abnormal test points. Outcome measurements of NFLT were total average NFLT, quadrant NFLT and 12 clock-hour NFLT. 12 clock-hour NFLT sectors were divided into 2 groups, superior sectors(10, 11, 12, 1, 2 clock hour sector) and inferior sectors(4, 5, 6, 7, 8 clock hour sector). These parameters were classified into 3 grades. In each glaucoma stage, the ratio of these 3 grades was calculated. Additionally, relationships between upper hemi-visual field and inferior sectors, lower hemi-visual field and superior sectors were investigated.
In glaucoma suspect, 56% subjects were within normal limit with total average NFLT. More than 80% subjects were within 5% tile limit and 33% subjects were within 1% tile limit with quadrant NFLT. In patients with early stage, 40% subjects were within normal limit with total average NFLT and more than 80% subjects were within 5% tile limit. FDT, Flicker perimetry and SWAP have more abnormal points than SAP with upper and lower hemi-visual field with 5% tile limit of inferior and superior NFLT sectors.
Abnormal criteria of cirrus OCT is useful to detect glaucoma changes. In 5%tile NFLT sectors, FDT, Flicker perimetry and SWAP detect more abnormal points than SAP.
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