April 2011
Volume 52, Issue 14
ARVO Annual Meeting Abstract  |   April 2011
Continuous Scale Probability Plot Analysis For Normals, Ocular Hypertensives, Glaucomatous Optic Neuropathies And Glaucomas
Author Affiliations & Notes
  • Donatella Caprino
    University of Rome Sapienza, Rome, Italy
  • Chris Johnson
    University of Iowa Hospital and Clinics, Iowa City, Iowa
  • Michael Wall
    Department of Neurology, University of Iowa, College of Medicine, Iowa City, Iowa
  • Footnotes
    Commercial Relationships  Donatella Caprino, None; Chris Johnson, None; Michael Wall, None
  • Footnotes
    Support  VA Merit Review Grant (to MW)
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5501. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Donatella Caprino, Chris Johnson, Michael Wall; Continuous Scale Probability Plot Analysis For Normals, Ocular Hypertensives, Glaucomatous Optic Neuropathies And Glaucomas. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5501.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

To evaluate perimetric cumulative probabilities for the 5% 10% 15% and 20% normal probability levels in eyes whose optic nerves were determined to be normal in minimal risk subjects, suspicious of glaucomatous changes, exhibiting glaucomatous optic neuropathy, and demonstrating glaucomatous damage.


A normative database consisting of 305 subjects between the ages of 10 and 92 was used to generate cumulative sensitivity probabilities (0 to 100 percentile), adjusted to a median age of 45 years. The number of visual field locations that had sensitivities below the 5, 10, 15 and 20 percentiles were determined for 212 eyes of normal control subjects (N), 134 eyes of ocular hypertensives with normal visual fields and optic discs (OH), 87 eyes of glaucoma suspects with normal visual fields and glaucomatous optic neuropathies (S), and 42 eyes of patients with glaucomatous visual field loss and optic neuropathies (GL).


The figure below shows the number of visual field locations (mean, s.d.) for the 4 groups at the 5% (upper left), 10% (upper right), 15% (lower left) and 20% (lower right) probability levels. For the probability levels of 5,10, 15 and 20 percentile, there was a significant difference in the number of locations outside of these normal probability values as a function of the groups (Kruskal Wallis test, p< 0.0002 for all comparisons). Paired comparisons among the groups indicated that for all probability levels, there was no significant difference in the number of locations between the N and OH eyes, the N and S eyes, and the OH and S eyes, with the exception of the 1% level, where the N and OH eyes demonstrated a significant difference. For all probability levels, there were significant differences between the number of locations for the N and G eyes, the OH and G eyes and the S and G eyes.


Our findings indicate that perimetric continuous scale probability plots reveal significant visual field differences among the continuum of normal to glaucoma groups.  

Keywords: perimetry • visual fields • optic disc 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.