April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Spectrum Of Fungal Isolates In Culture Proven Exogenous Fungal Endophthalmitis
Author Affiliations & Notes
  • Ruwan A. Silva
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • Charles C. Wykoff
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • Darlene Miller
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
  • Harry W. Flynn, Jr.
    Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5613. doi:
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      Ruwan A. Silva, Charles C. Wykoff, Darlene Miller, Harry W. Flynn, Jr.; Spectrum Of Fungal Isolates In Culture Proven Exogenous Fungal Endophthalmitis. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5613.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To report the fungal species isolated from ocular specimens in a large series of patients with exogenous fungal endophthalmitis.

Methods: : Retrospective, single institution, consecutive case series. The microbiologic and medical records of all patients treated at the Bascom Palmer Eye Institute between January 1, 1990, and June 30, 2010, for culture-proven exogenous fungal endophthalmitis were reviewed.

Results: : Culture-positive exogenous fungal endophthalmitis occurred in 72 eyes, including 29 cases (40%) associated with fungal keratitis and 33 cases (46%) occurring after penetrating ocular trauma or intraocular surgery. Filamentous fungi (molds) accounted for 55 cases (76%), and Candida species (yeasts) accounted for 17 cases (24%). Although most keratitis cases were caused by Fusarium (19 of 29; 66%), open-globe cases were caused by a broader spectrum of fungi.

Conclusions: : This report highlights the differences between the clinical categories of exogenous fungal endophthalmitis. Although 76% of all cases were caused by molds, most commonly Fusarium and Aspergillus, the most common fungal species varied by clinical category.

Keywords: fungal disease • vitreous • vitreoretinal surgery 
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