April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Reliability Of Vessel Diameter Measurements With A Retinal Oximeter
Author Affiliations & Notes
  • Einar Stefansson
    Ophthalmology, University of Iceland, Reykjavik, Iceland
    Oxymap ehf, Reykjavik, Iceland
  • Renata Blondal
    Oxymap ehf, Reykjavik, Iceland
  • Margret K. Sturludottir
    Oxymap ehf, Reykjavik, Iceland
  • Sveinn H. Hardarson
    Ophthalmology, University of Iceland, Reykjavik, Iceland
  • Gisli H. Halldorsson
    Oxymap ehf, Reykjavik, Iceland
  • Footnotes
    Commercial Relationships  Einar Stefansson, Oxymap ehf (I, P); Renata Blondal, Oxymap ehf (E); Margret K. Sturludottir, Oxymap ehf (E); Sveinn H. Hardarson, Oxymap ehf (I); Gisli H. Halldorsson, Oxymap ehf (I, E, P)
  • Footnotes
    Support  Icelandic Research Council
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5663. doi:
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      Einar Stefansson, Renata Blondal, Margret K. Sturludottir, Sveinn H. Hardarson, Gisli H. Halldorsson; Reliability Of Vessel Diameter Measurements With A Retinal Oximeter. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5663.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : The purpose of the study was to test the reliability of vessel diameter measurements with a newly developed retinal oximeter.

Methods: : Twelve healthy individuals participated in the study. Retinal images were taken with the Oxymap Retinal Oximeter (Oxymap ehf. Reykjavik, Iceland). Diameters of retinal vessels were measured automatically with the Oxymap Analyzer software. Repeated measurements on the same vessel segments were compared. The automatic measurements were also compared with semi-automatic measurements with an add-on to the ImageJ software http://rsbweb.nih.gov/ij/

Results: : Variance coefficient (standard deviation / mean) from the repeatability test was 2.8% and 4.0% for first and second degree venules and 3.5% and 5.4% for first and second degree arterioles, respectively. ImageJ measured larger mean diameters than Oxymap Analyzer in all cases and the differences were 5.1±2.2, 2.9±1.3 and 2.7±1.6 pixels for first, second and third degree venules and 3.1±1.2, 2.7±0.9 and 2.9±1.4 pixels for first, second and third degree arterioles (mean ±standard deviation, n=12). The difference between the programs was significant (p<0.05 except for third degree venules).

Conclusions: : Vessel diameter measurements with the oximeter are repeatable and comparison with an established method demonstrates a relatively stable offset where the standard deviation of the difference is rather small. Different definitions of vessel borders may be the reason for this difference.

Keywords: blood supply • imaging/image analysis: non-clinical • ischemia 
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