Abstract
Purpose: :
To compare the effect of two intraocular irrigating solutions BSS® and Dextrose-Bicarbonate-Lactated Ringers (DBLR) on corneal endothelium cell density and central corneal thickness after phacoemulsification on cataract surgery.
Methods: :
This prospective study comprised 44 consecutive patients with age-related cataract who were randomly allocated to either Group 1, (n=22) with BSS® or Group 2, (n=22) with DBLR as intraoperative irrigating solution. Endothelial cell density (ECD) and central corneal thickness (CCT) were measured by specular microscopy (SP- 2000 by TOPCON,Inc) at preoperative and 2 and 30 days after surgery. Groups were well balanced regarding age, ECD and CCT (p>0.05). Data was compared using Student t test.
Results: :
In evaluation performed 2 days after surgery the ECD did not differ significantly in both groups 3.895 ± 27.20% and 4.196 ±15,75%.(p=0,2016). As well, in the 30-day the results were similarly, -8.794 ±23.34% and -3.251 ±25.34%.(p=0.5427) for group 1 and 2 respectively.The mean difference in central corneal thickness with two days after surgery was 51.35 ± 45.68 and 36.11 ± 24.76 (p = 0.2051) and 30 days after surgery was 7.500 ± 12.69 and 3.654 (± 21.32) (p = 0.4975) for the solutions BSS® and DBLR groups.
Conclusions: :
The solutions BSS ® and Dextrose Bicarbonate-lactated Ringer (DBLR) showed comparable effects on postoperative corneal endothelial cell density and corneal thickness when evaluated at 2 and 30 days after phacoemulsification cataract surgery, suggesting that both solutions have similar properties to preserve the integrity of the cornea.
Keywords: cornea: endothelium • cataract • edema