April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Safety Profile of Preservatives-Containing Intracameral Phenylephrine
Author Affiliations & Notes
  • Dimitrios Raptakis
    Department of Ophthalmology, Venizeleion General Hospital of Heraklion, Greece, Heraklion, Greece
  • Anastasios Stavrakakis
    Department of Ophthalmology, Venizeleion General Hospital of Heraklion, Greece, Heraklion, Greece
  • Theoni Panagiotoglou
    Department of Ophthalmology, Venizeleion General Hospital of Heraklion, Greece, Heraklion, Greece
  • Nikolaos Avgoustinakis
    Department of Ophthalmology, Venizeleion General Hospital of Heraklion, Greece, Heraklion, Greece
  • George Pappas
    Department of Ophthalmology, Venizeleion General Hospital of Heraklion, Greece, Heraklion, Greece
  • Charalambos Fanourgiakis
    Department of Ophthalmology, Venizeleion General Hospital of Heraklion, Greece, Heraklion, Greece
  • Footnotes
    Commercial Relationships  Dimitrios Raptakis, None; Anastasios Stavrakakis, None; Theoni Panagiotoglou, None; Nikolaos Avgoustinakis, None; George Pappas, None; Charalambos Fanourgiakis, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 5688. doi:
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      Dimitrios Raptakis, Anastasios Stavrakakis, Theoni Panagiotoglou, Nikolaos Avgoustinakis, George Pappas, Charalambos Fanourgiakis; Safety Profile of Preservatives-Containing Intracameral Phenylephrine. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5688.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the efficacy and safety of intracameral use of phenylephrine with preservatives , in order to achieve adequate perioperative dilation.

Methods: : This is a case series of 96 patients who underwent cataract surgery and the pupil was not dilated well . We injected intracameral phenylephrine 5% with preservative (benzalkonium) in a 10% dilution. Patients were examined preoperatively , 1 week and 1 month after surgery, with endothelioscopy, biomicroscopy, fundoscopy and optical coherence tomography. We used a control group of 96 patients where minims phenylephrine were used.

Results: : No complications were observed in the treatment group. No case of endophthalmitis was observed.

Conclusions: : Intracameral phenylephrine is equally safe with or without preservatives and provides adequate and fast dilation during cataract surgery.

Keywords: cataract • pupil • ocular irritancy/toxicity testing 
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