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Dimitrios Raptakis, Anastasios Stavrakakis, Theoni Panagiotoglou, Nikolaos Avgoustinakis, George Pappas, Charalambos Fanourgiakis; Safety Profile of Preservatives-Containing Intracameral Phenylephrine. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5688.
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To evaluate the efficacy and safety of intracameral use of phenylephrine with preservatives , in order to achieve adequate perioperative dilation.
This is a case series of 96 patients who underwent cataract surgery and the pupil was not dilated well . We injected intracameral phenylephrine 5% with preservative (benzalkonium) in a 10% dilution. Patients were examined preoperatively , 1 week and 1 month after surgery, with endothelioscopy, biomicroscopy, fundoscopy and optical coherence tomography. We used a control group of 96 patients where minims phenylephrine were used.
No complications were observed in the treatment group. No case of endophthalmitis was observed.
Intracameral phenylephrine is equally safe with or without preservatives and provides adequate and fast dilation during cataract surgery.
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