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Michael C. Mrochen, Arthur Cummings, Matthias Maus, Theo Seiler; Optical Ray Tracing-Guided LASIK for Moderate to High Myopic Astigmatism. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5755.
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This study assesses the efficacy, safety and predictability of a highly individualized LASIK ablation profile based on an optical ray tracing algorithm for the treatment of moderate to high myopic astigmatism.
In this multicenter study, three centers enrolled 127 eyes (71 patients) with a manifest refraction sphere ranging from 0.5 to -10.25 D (mean -5.92±1.72 D), with astigmatism ranging from 0 to -4.5 D. The intended outcome was plano in most eyes, an overcorrection of 0.5 D in one eye and an overcorrection of 0.25 D in 2 eyes. Refractive outcomes were analyzed pre-operatively and at 1 day, 1 month and 3 months post-operatively.
At three months post-operatively, 15 eyes had been lost to follow-up and one eye was excluded from analysis because of an early retreatment. From the remaining 111, 93 (83.8%) had an uncorrected visual acuity of 20/20 or better. The mean manifest refraction spherical equivalent (MRSE) for all eyes was 0.03±0.30 D. In 97 of 111 eyes (87.4%), the MRSE was within ±0.5 D, and in 107 of 111 eyes, (96.4%) the MRSE was within ±1 D. No eye lost 2 or more lines in the best spectacle corrected visual acuity.
The new algorithm, which uses optical ray tracing to calculate highly individualized ablation profiles for LASIK treatment of moderate to high myopic astigmatism, is efficacious, safe and predictable.
Clinical Trial: :
Swissmedic, BFARM, IMB, ray traing study
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