Abstract
Purpose: :
This study assesses the efficacy, safety and predictability of a highly individualized LASIK ablation profile based on an optical ray tracing algorithm for the treatment of moderate to high myopic astigmatism.
Methods: :
In this multicenter study, three centers enrolled 127 eyes (71 patients) with a manifest refraction sphere ranging from 0.5 to -10.25 D (mean -5.92±1.72 D), with astigmatism ranging from 0 to -4.5 D. The intended outcome was plano in most eyes, an overcorrection of 0.5 D in one eye and an overcorrection of 0.25 D in 2 eyes. Refractive outcomes were analyzed pre-operatively and at 1 day, 1 month and 3 months post-operatively.
Results: :
At three months post-operatively, 15 eyes had been lost to follow-up and one eye was excluded from analysis because of an early retreatment. From the remaining 111, 93 (83.8%) had an uncorrected visual acuity of 20/20 or better. The mean manifest refraction spherical equivalent (MRSE) for all eyes was 0.03±0.30 D. In 97 of 111 eyes (87.4%), the MRSE was within ±0.5 D, and in 107 of 111 eyes, (96.4%) the MRSE was within ±1 D. No eye lost 2 or more lines in the best spectacle corrected visual acuity.
Conclusions: :
The new algorithm, which uses optical ray tracing to calculate highly individualized ablation profiles for LASIK treatment of moderate to high myopic astigmatism, is efficacious, safe and predictable.
Clinical Trial: :
Swissmedic, BFARM, IMB, ray traing study
Keywords: refractive surgery: LASIK • refractive surgery: optical quality • refractive surgery: other technologies