April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Morphology And Function Of Macula After Successful Surgery For Acute Macular-off Rhegmatogenous Retinal Detachment
Author Affiliations & Notes
  • Satoshi Mizuno
    Department of Ophthalmology and Visual Science, Chiba, Japan
  • Takayuki Baba
    Department of Ophthalmology and Visual Science, Chiba, Japan
  • Tomoaki Tatsumi
    Department of Ophthalmology Teikyo University, Chiba, Japan
  • Akira Hagiwara
    Ophthalmology,
    Department of Ophthalmology and Visual Science, Chiba, Japan
  • Eiju Sato
    Department of Ophthalmology and Visual Science, Chiba, Japan
  • Shuichi Yamamoto
    Department of Ophthalmology,
    Department of Ophthalmology and Visual Science, Chiba, Japan
  • Footnotes
    Commercial Relationships  Satoshi Mizuno, None; Takayuki Baba, None; Tomoaki Tatsumi, None; Akira Hagiwara, None; Eiju Sato, None; Shuichi Yamamoto, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 6141. doi:
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      Satoshi Mizuno, Takayuki Baba, Tomoaki Tatsumi, Akira Hagiwara, Eiju Sato, Shuichi Yamamoto; Morphology And Function Of Macula After Successful Surgery For Acute Macular-off Rhegmatogenous Retinal Detachment. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6141.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To examine the morphological and functional changes of the macula after successful surgery for an acute macular-off rhegmatogenous retinal detachment (RRD).

Methods: : Thirteen eyes of 13 acute macula-off RRD cases were studied (11 men, 2 women). The mean age of the patients was 54.0 years with a range from 28 to 68 years. The interval between the decrease in vision to surgery was <7 days in all cases. This study was approved by the Institutional Review Board, and an informed consent was obtained from every patients. Three months after the RD surgery, the thickness of the ganglion cell complex (GCC) and outer retina was determined by FD-OCT (RTVue-100, Optovue), the retinal sensitivity was measured by a microperimetry (MP-1, NIDEK), and the amplitudes of P1 and PhNR of the mfERGs in the central 10 degrees were recorded. The values were compared with those obtained from the unaffected fellow eyes. Cases with any other ocular disorders were excluded.

Results: : The retina was reattached in all eyes with two eyes treated by scleral buckling and 9 eyes with pars plana vitrectomy. The GCC and outer retinal thicknesses of the macula at 3 months after surgery were not significantly different from that of the unaffected eyes (P=0.225 and 0.123). The retinal sensitivity of the central 10 degree of the RRD eyes was lower than that of the unaffected eyes although the difference was not statistically significant (P=0.068). The amplitude of P1 in the operated eyes was 12.8 nV/deg, which was significantly smaller than that of the unaffected eyes (P=0.005). The PhNR/P1 ratio was 0.31 in the treated eyes which was smaller than that in the fellow eyes (0.47).

Conclusions: : The morphological changes of macula at 3 months after successful surgery for macular-off RRD were minimal. On the other hand, the retinal sensitivity was slightly reduced for both the outer and inner retina, and the retinal neurons generating the mfERGs were not fully recovered. There was a dissociation of morphological and functional recovery of macular after macular-off RRD surgery at 3 months.

Keywords: retinal detachment • vitreoretinal surgery • electroretinography: clinical 
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