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Qianying Gao, Xiaofeng Lin, Zhenfang Wang, Zhaoxin Jiang, Chongde Long, Yaqin Liu, Peijuan Wang, Changxian Yi, Chenjin Jin, Xvyuan Sun; Efficacy And Safety Of A Silicone Oil-filled Foldable Capsular Vitreous Body In The Treatment Of Severe Retinal Detachment. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6167.
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To determine the efficacy and safety of a silicone oil-filled foldable capsular vitreous body (FCVB) in the treatment of severe retinal detachment in human eyes.
The study enrolled three eyes of three patients. A standard three-port pars plana vitrectomy was performed, and FCVB was triple-folded and sent into the vitreous cavity, then silicone oil was injected into the capsule to support the retina. The treated eyes were examined using goldmann applanation tonometry, noncontact specular microscopy, fundus photography, optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM) during a nine-month follow-up appointment.
The FCVB can easily be implanted into the vitreous cavity through a three-mm incision and can easily be removed through a 3×0.5 mm scleral incision. Retinal attachment was found in three eyes at the nine-month examination. The fundus and OCT showed that the FCVB was well distributed in the vitreous cavity and evenly supported the retina. The IOP after FCVB implantation did not show a significant decrease compared with those of preoperative eyes. UBM showed that the FCVB smoothly contacted the ciliary body and did not crush it.
Silicone oil-filled FCVB was shown to be effective and safe in 3 eyes as a vitreous substitute over a nine-month observation time.
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