April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Efficacy And Safety Of A Silicone Oil-filled Foldable Capsular Vitreous Body In The Treatment Of Severe Retinal Detachment
Author Affiliations & Notes
  • Qianying Gao
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Xiaofeng Lin
    Traumatic Department,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Zhenfang Wang
    Traumatic Department,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Zhaoxin Jiang
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Chongde Long
    Traumatic Department,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Yaqin Liu
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Peijuan Wang
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Changxian Yi
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Chenjin Jin
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Xvyuan Sun
    State Key Lab of Ophthalmology,
    Zhongshan Ophthalmic Center, Guangzhou, China
  • Footnotes
    Commercial Relationships  Qianying Gao, ZL200810199177.3 (P); Xiaofeng Lin, None; Zhenfang Wang, None; Zhaoxin Jiang, None; Chongde Long, None; Yaqin Liu, None; Peijuan Wang, None; Changxian Yi, None; Chenjin Jin, None; Xvyuan Sun, None
  • Footnotes
    Support  863 Program, 2009AA2Z404
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 6167. doi:https://doi.org/
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      Qianying Gao, Xiaofeng Lin, Zhenfang Wang, Zhaoxin Jiang, Chongde Long, Yaqin Liu, Peijuan Wang, Changxian Yi, Chenjin Jin, Xvyuan Sun; Efficacy And Safety Of A Silicone Oil-filled Foldable Capsular Vitreous Body In The Treatment Of Severe Retinal Detachment. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6167. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the efficacy and safety of a silicone oil-filled foldable capsular vitreous body (FCVB) in the treatment of severe retinal detachment in human eyes.

Methods: : The study enrolled three eyes of three patients. A standard three-port pars plana vitrectomy was performed, and FCVB was triple-folded and sent into the vitreous cavity, then silicone oil was injected into the capsule to support the retina. The treated eyes were examined using goldmann applanation tonometry, noncontact specular microscopy, fundus photography, optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM) during a nine-month follow-up appointment.

Results: : The FCVB can easily be implanted into the vitreous cavity through a three-mm incision and can easily be removed through a 3×0.5 mm scleral incision. Retinal attachment was found in three eyes at the nine-month examination. The fundus and OCT showed that the FCVB was well distributed in the vitreous cavity and evenly supported the retina. The IOP after FCVB implantation did not show a significant decrease compared with those of preoperative eyes. UBM showed that the FCVB smoothly contacted the ciliary body and did not crush it.

Conclusions: : Silicone oil-filled FCVB was shown to be effective and safe in 3 eyes as a vitreous substitute over a nine-month observation time.

Clinical Trial: : http://www.chictr.org ChiCTR-TNC-00000396

Keywords: vitreous substitutes • retinal detachment 
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