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Jonghyun Lee, Doh Lee, Suk Kyue Choi, Jin Hyoung Kim; Surface Calcification of Hydrophilic Acrylic Intraocular Lens Related To Neovacular Glaucoma: 9 Cases With Rayner C-flex 570c. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6210.
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© ARVO (1962-2015); The Authors (2016-present)
To report 9 cases with anterior surface calcification of Rayner C-flex 570C, all of which occurred in eyes with neovascular glaucoma.
We present 9 cases in 8 patients with neovascular glaucoma where intraocular lens opacification due to calcification occurred. We investigated clinical characteristics of the cases.
All 9 eyes’ IOLs were implanted between July 2006 and August 2009. Complaints of decreased visual function occurred 14 to 30 months after implantation. All patients were under anti-glaucoma medication because of neovascular glaucoma. Mutiple fine, translucent, spherical-ovoid or cerebriform granules were found in the anterior surface of the optic of the intraocular lens. Intraocular lens exchange was performed in two cases, and the explanted intraocular lenses were sent for histopathologic analysis. Scanning electron microscopy and energy-dispersive X-ray analysis confirmed the presence of calcium and phosphate within the deposits of anterior surface of the IOL.
It may be related to an inflammation and breakdown of the blood-aqeous barrier in neovascular glaucoma leading to precipitation of calcium. Careful consideration should be taken when using this hydrophilic acrylic intraocular lens in patients with risk of neovascular glaucoma like diabetes, central retinal vein occlusion.
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