April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Non-Invasive In-Situ Power Adjustment Of Intraocular Lenses By Refractive Index Shaping
Author Affiliations & Notes
  • Ruth Sahler
    Medical Physics, University of Heidelberg, Mannheim, Germany
    Aaren Scientific Inc, Irvine, California
  • Josef F. Bille
    Medical Physics, University of Heidelberg, Mannheim, Germany
  • Stephen Zhou
    Aaren Scientific Inc, Irvine, California
  • Rick Aguilera
    Aaren Scientific Inc, Irvine, California
  • David J. Schanzlin
    Shiley Eye Center, UCSD, San Diego, California
  • Footnotes
    Commercial Relationships  Ruth Sahler, Aaren Scientific Inc (E); Josef F. Bille, Aaren Scientific Inc (C, P), Heidelberg Engineering (C, P); Stephen Zhou, Aaren Scientific Inc (E); Rick Aguilera, Aaren Scientific Inc (I, E); David J. Schanzlin, Aaren Scientific Inc (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 6241. doi:
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    • Get Citation

      Ruth Sahler, Josef F. Bille, Stephen Zhou, Rick Aguilera, David J. Schanzlin; Non-Invasive In-Situ Power Adjustment Of Intraocular Lenses By Refractive Index Shaping. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6241.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Refractive Index Shaping (RIS) can be used for customized power adjustments using high repetition rate and focused femtosecond pulses.

Methods: : Focused femtosecond laser pulses can increase the refractive index of the lens material by approximately 0.01. Various dopants and their concentrations have been investigated to identify the factors which can significantly impact the RIS speed.

Results: : The results show that the power of the femtosecond laser has the highest impact on the RIS speed. An increase in yellow dye and the UV absorber percentage enhances the RIS speed significantly at low laser power levels due to the thermal effect and its effectiveness decreases considerably at high power lasers, such as the 500mW fiber laser, due to the dominant ionisation mechanism.

Conclusions: : Results suggest that customized IOL power adjustments are possible using focused femtosecond laser pulses.

Keywords: cataract • intraocular lens • laser 
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