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Ruth Sahler, Josef F. Bille, Stephen Zhou, Rick Aguilera, David J. Schanzlin; Non-Invasive In-Situ Power Adjustment Of Intraocular Lenses By Refractive Index Shaping. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6241.
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Refractive Index Shaping (RIS) can be used for customized power adjustments using high repetition rate and focused femtosecond pulses.
Focused femtosecond laser pulses can increase the refractive index of the lens material by approximately 0.01. Various dopants and their concentrations have been investigated to identify the factors which can significantly impact the RIS speed.
The results show that the power of the femtosecond laser has the highest impact on the RIS speed. An increase in yellow dye and the UV absorber percentage enhances the RIS speed significantly at low laser power levels due to the thermal effect and its effectiveness decreases considerably at high power lasers, such as the 500mW fiber laser, due to the dominant ionisation mechanism.
Results suggest that customized IOL power adjustments are possible using focused femtosecond laser pulses.
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