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Eun Ji Lee, Tae-Woo Kim, Robert N. Weinreb, Ki Ho Park, Seok Hwan Kim, Dong Myung Kim; Central Corneal Thickness, Axial Length and the Thickness of the Lamina Cribrosa in Normal Human Eyes. Invest. Ophthalmol. Vis. Sci. 2011;52(14):6258.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate whether thin cornea and longer axial length are associated with thinner lamina cribrosa thickness in healthy human eyes.
Optic discs of the 189 healthy eyes were scanned using enhanced depth imaging spectral domain optical coherence tomography. The thickness of lamina cribrosa was measured on B scan images obtained at the center of the optic nerve head. Logistic regression analysis was used to determine the factors associated with the lamina cribrosa thickness.
The mean thickness of the lamina cribrosa was 387.0±60.49 µm (range: 89.01 to 387.0 µm). Multivariate analysis showed significant influence of older age on increased lamina cribrosa thickness (P=0.012). There was no significant association between the lamina cribrosa thickness and central corneal thickness or axial length.
In healthy human eyes, lamina cribrosa thickness increased significantly with older age. Neither the central corneal thickness nor the axial length was significantly associated with lamina cribrosa thickness.
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