Abstract
Purpose: :
To investigate the effect of laser peripheral iridotomy (LPI) on controlling intraocular pressure (IOP) and progression of angle closure in Vietnamese.
Methods: :
Medical records of Vietnamese patients who were examined during the period from January 2004 to November 2008, and diagnosed as primary angle-closure suspect (PACS), primary angle-closure (PAC), or primary angle closure glaucoma (PACG) and who had received LPI, were reviewed. Clinical outcomes and ocular features were analyzed.
Results: :
Two hundred patients (372 eyes) with a mean follow-up period of 8.0 ± 4.3 years were included in this study. The proportions of eyes which required additional treatments (medical, laser, or surgical) to control IOP were 15/197 (7.6%), 67/126 (53.2%), and 45/49 (91.8%) eyes in the PACS, PAC, and PACG groups, respectively. No eyes in the PACS group needed further laser or surgery. However, 8/126 (6.3%) and 17/49 (34.7%) of eyes in the PAC and PACG groups, respectively, had undergone filtration surgery. Four PACS (1.1%) eyes progressed to PAC; four PACS (1.1%) eyes progressed to PACG; and eight PAC (2.2%) eyes progressed to PACG. No significant difference in anterior chamber depth, lens thickness, axial length, lens/axial length factor, and relative lens position was found between eyes with and without progression.
Conclusions: :
Further medications, laser, or surgery are required to control IOP after LPI for eyes with primary angle-closure, especially for eyes with PACG. Close follow up and appropriate therapies for these patients is warranted to prevent progression of disease.
Keywords: clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • intraocular pressure • laser