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P.-H. Peng, N. Nguyen, H. Nguyen, S. Lin; The Effect of Laser Peripheral Iridotomy in Vietnamese Patients With Primary Angle-Closure. Invest. Ophthalmol. Vis. Sci. 2009;50(13):162.
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To investigate the effect of laser peripheral iridotomy (LPI) on controlling intraocular pressure (IOP) and progression of angle closure in Vietnamese.
Medical records of Vietnamese patients who were examined during the period from January 2004 to November 2008, and diagnosed as primary angle-closure suspect (PACS), primary angle-closure (PAC), or primary angle closure glaucoma (PACG) and who had received LPI, were reviewed. Clinical outcomes and ocular features were analyzed.
Two hundred patients (372 eyes) with a mean follow-up period of 8.0 ± 4.3 years were included in this study. The proportions of eyes which required additional treatments (medical, laser, or surgical) to control IOP were 15/197 (7.6%), 67/126 (53.2%), and 45/49 (91.8%) eyes in the PACS, PAC, and PACG groups, respectively. No eyes in the PACS group needed further laser or surgery. However, 8/126 (6.3%) and 17/49 (34.7%) of eyes in the PAC and PACG groups, respectively, had undergone filtration surgery. Four PACS (1.1%) eyes progressed to PAC; four PACS (1.1%) eyes progressed to PACG; and eight PAC (2.2%) eyes progressed to PACG. No significant difference in anterior chamber depth, lens thickness, axial length, lens/axial length factor, and relative lens position was found between eyes with and without progression.
Further medications, laser, or surgery are required to control IOP after LPI for eyes with primary angle-closure, especially for eyes with PACG. Close follow up and appropriate therapies for these patients is warranted to prevent progression of disease.
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