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C. C. Shen, S. Salim, A. Lupinacci, P. Netland; Comparative Study of Trabeculectomy with Mitomycin C vs. Ahmed Glaucoma Valve in Neovascular Glaucoma. Invest. Ophthalmol. Vis. Sci. 2009;50(13):175.
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To compare post-surgical outcomes in neovascular glaucoma (NVG) patients who underwent trabeculectomy with mitomycin C versus Ahmed Glaucoma Valve (AGV) implant.
Retrospective comparative case series. Reviewed 40 eyes of 40 patients with underlying diagnosis of NVG, divided into two groups: Ahmed valve (N=20) and trabeculectomy with MMC (N=21) All cases done at single institution and cross-matched by age, race, and gender. Surgical success defined as 6 mmHg ≤ IOP ≤ 21 mmHg, with or without the use of glaucoma medications, and light perception or better vision.
The average follow-up was 7.9±2.3 months for the AGV group and 8.2±2.5 months for the trabeculectomy group (p=0.674). No statistically significant difference between the groups was observed in terms of the etiology of NVG and the degree of angle closure preoperatively. Preoperative mean intraocular pressure (IOP) and visual acuity were similar in both groups. Rate of surgical success was 76.2% in the Ahmed group versus 61.9% in the trabeculectomy group (p=0.317). The mean number of postoperative glaucoma medications in the Ahmed group was 0.7±1.3 versus 1.6±1.6 in the trabeculectomy group (p=0.051).
These results indicate that short-term post-surgical outcomes are similar between Ahmed Glaucoma Valve and trabeculectomy with mitomycin C in patients with neovascular glaucoma.
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