Abstract
Purpose: :
There is a clinical impression that postoperative complications such as shallow anterior chamber/hypotony and malignant glaucoma are more common after glaucoma surgery performed for eyes with primary angle closure (PACG) compared to primary open angle glaucoma (POAG). The aim of this study was to compare postoperative complications after glaucoma surgery for PACG and POAG patients.
Methods: :
We retrospectively analyzed postoperative complications within the first year in all subjects who underwent glaucoma surgery for PACG and POAG at the Singapore National Eye Centre over a 5-year period. The types of glaucoma surgeries included trabeculectomy and phacotrabeculectomy, all with anti-metabolites (Mitomycin-C or 5-Fluorouracil).
Results: :
A total of 530 subjects with PACG (131 trabeculectomy and 399 phacotrabeculectomy) and 993 POAG (255 trabeculectomy and 738 phacotrabeculectomy) were included. Overall, postoperative complications occurred in 24/530 (4.5%; 95% CI: 2.99-6.56) PACG and 36/993 (3.6%; 95% CI: 2.59-4.93) POAG subjects (P = 0.38). The rate of overfiltration/hypotony (PACG 2.3%; 95% CI: 1.23-3.82 vs POAG 1.1%; 95% CI: 0.58-1.92; P = 0.08), malignant glaucoma (PACG 0%; 95% CI: 0-0.56 vs POAG 0.1%; 95% CI: 0.01-0.5; P = 1.0), bleb leak (PACG 0.6%; 95% CI: 0.14-1.53 vs POAG 0.8%; 95% CI: 0.37-1.52; P = 0.55) and endophthalmitis (PACG 0.4%; 95% CI: 0.06-1.24 vs POAG 0.3%; 95% CI: 0.08-0.82, P = 1.0) were similar in the 2 groups.
Conclusions: :
In this large sample of 1523 Asian subjects, the rate of postoperative complications within the first year after glaucoma surgery was found to be low and similar in PACG and POAG subjects.
Keywords: clinical (human) or epidemiologic studies: outcomes/complications