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S. Kesting, D. H. Kauffmann Jokl, R. T. Smith, J. van Meurs, M. Busuioc; Macular Drusen After Peripheral Laser Treatment. Invest. Ophthalmol. Vis. Sci. 2009;50(13):187.
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To report the 2 year findings of the effect upon central macular drusen in eyes treated with peripheral laser photocoagulation.
14 patients with bilateral central macular drusen and normal acuity had one eye treated with 200 argon laser spots (500 micron diameter) in the anterior- superior retinal quadrant. Pre and post-operative drusen area were determined by an established digital protocol, and the findings were verified by double masked observers. The untreated eye was the control.
The central drusen area for the treated eyes showed in 4 eyes minimal change (less than 10%), in 8 eyes a significant decrease and in 2 eyes a significant increase (significant = 20% or more). The control eyes showed in 3 eyes minimal change, in 5 eyes a significant decrease and in 6 eyes a significant increase. The net effect for each patient upon the summed central drusen area (OD plus OS) showed 3 patients to be minimally changed, 5 patients to show a slight increase (10 to 20%), and 6 patients to show a slight decrease. No CNV was noted and visual acuity remained unaltered in treated and control eyes.
Peripheral laser treatment may affect the course of central macular drusen in both the treated and the untreated eye. Further prospective investigation of these effects is warranted.
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