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S. Lee, M. Shin, B. Oum, J. Lee; Cytokines in Vitreous of Rabbits After Photocoagulation Using Conventional and Short Pulse Pattern Scanning Laser. Invest. Ophthalmol. Vis. Sci. 2009;50(13):209.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the effect of photocoagulation using between conventional laser and short pulse pattern scanning laser.
Laser photocoagulation was performed using conventional in the right eye and pattern scanning laser in left eye of eight pigmented rabbit. The spot diameter was 400 µm and the exposure time was 0.1 and 0.02 seconds respectively. The power was adjusted for mild to moderate burns which were similar visually. A hundred burns were made for each eye. Vitreous humor was aspirated before, at 1, 3 and 7 days after the photocoagulation. IL-1, IL-6, IL-8 and TNF- were measured in five rabbits. Specimens for histological examinations were obtained at 1, 3 and 7 days.
Ophthalmoscopic findings were similar in both lasers. The ranges of power were 175-225 mW in conventional laser and 400-500 mW in pattern scanning laser. IL-6, IL-8 and TNF- has increased significantly in both groups at 1, 3 and 7 days (p<0.05), while there was no significant difference between two groups. Histological findings were similar in the both eyes.
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