Abstract
Purpose: :
To evaluate the effect of supplementation on non-advanced dry macular degeneration (DAMD) retinal function.
Methods: :
Multifocal electroretinogram (MERG) at baseline, 2 months, and 2 year follow-up of 10 eyes without supplementation were compared to 10 eyes placed on daily high dose Beta-carotene, Vitamin C, Vitamin E, Zinc, Copper, Lutein, and Zeaxanthin.
Results: :
At 2 month and 2 year follow-up, amplitude densities were unchanged in the control group, while the supplementation group improved in amplitude density in the N1 (P=.002) and P1 (P=.002) waves in all six rings.
Keywords: age-related macular degeneration • antioxidants • carotenoids/carotenoid binding proteins