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M.-H. Sun, L.-Y. Kao, H.-S. Wang; Optic Neuritis in Children. Invest. Ophthalmol. Vis. Sci. 2009;50(13):283.
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To document the clinical presentation, associated systemic disease, and visual prognosis of pediatric optic neuritis in Chang Gung Memorial Hospital
60 children admitted for acute optic neuropathy were retrospectively reviewed in Chang Gung Memorial Hospital since 1998~2008. Optic neuritis was diagnosed on the basis of patient history, visual loss, relative afferent pupillary defect ( RAPD ) sign, color vision defect, and ancillary test including visual field (VF) and visual evoked potential (VEP) after excluding infectious, trauma, and compressive origin.
26 patients with total 42 eyes met the criteria for diagnosis of optic neuritis. Age at onset ranged from 5 years old to 17 years old. There was a female predilection (61.5%). Bilateral involvement was present in 64.5% of patients, disc swelling was present in 57.1% of patients. In view of systemic association, a preceding viral illness was present in 7 patients ( 30.4%). Among these associated systemic diseases, ADEM( acute disseminated encephalomyelitis ) is the most common associated disease. Final visual acuity over 20/40 was present in 23 eyes ( 67.6% ).
patients with bilateral involvement, disc swelling have more favorable visual outcome. Image study is needed in all children because associated systemic disease such as ADEM is common.
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