Abstract
Purpose: :
To investigate clinical features and visual outcome, and to identify prognostic factors in Korean patients with idiopathic retinal vasculitis.
Methods: :
Medical records of patients with idiopathic retinal vasculitis were reviewed retrospectively. Patients with evidences of systemic or other ocular diseases related to retinal vasculitis were excluded. Clinical features including age, gender, visual acuity, fundus findings, treatment methods, recurrences, and ocular complications were reported. Visual prognosis was evaluated by Kaplan-Meier survival analysis and relationships between potential risk factors and poor visual outcome were analyzed by Cox proportional hazards regression models.
Results: :
Forty Korean patients were included. Median age was 44 years (range, 15 to 63) and median follow-up was 24.5 months (range, 12 to 76). Diffuse vascular leak in fluorescein angiography was the most common fundus finding followed by cystoid macular edema and capillary nonperfusion. The cumulative risk of visual acuity 20/200 or worse and 20/60 or worse at 6 years was 7.4% and 23.8%, respectively. Poor visual outcome (20/60 or worse) were associated with poor initial visual acuity (20/200 or worse) and age under 45 years, but not with gender, two or more recurrences, cystoid macular edema, capillary nonperfusion, diffuse vascular leak, and neovascularization.
Conclusions: :
Overall visual outcome of idiopathic retinal vasculitis was good. Poor visual outcome was associated with initial visual acuity and young age, but not with angiographic features such as capillary nonperfusion and cystoid macular edema .
Keywords: uveitis-clinical/animal model