April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Complications After Intravitreal Bevacizumab (Avastin): Analysis of 5132 Injections
Author Affiliations & Notes
  • D. Moreno-Paramo
    Retina, APEC, Mexico, Mexico
  • A. Perez-Montesinos
    Retina, APEC, Mexico, Mexico
  • R. Velez-Montoya
    Retina, APEC, Mexico, Mexico
  • M. Martinez-Castellanos
    Retina, APEC, Mexico, Mexico
  • G. Garcia-Aguirre
    Retina, APEC, Mexico, Mexico
  • J. Dalma-Weiszhausz
    Retina, APEC, Mexico, Mexico
  • J. Jimenez-Sierra
    Retina, APEC, Mexico, Mexico
  • H. Quiroz-Mercado
    Retina, APEC, Mexico, Mexico
  • D. Ochoa-Contreras
    Retina, APEC, Mexico, Mexico
  • V. Morales-Canton
    Retina, APEC, Mexico, Mexico
  • Footnotes
    Commercial Relationships  D. Moreno-Paramo, None; A. Perez-Montesinos, None; R. Velez-Montoya, None; M. Martinez-Castellanos, None; G. Garcia-Aguirre, None; J. Dalma-Weiszhausz, None; J. Jimenez-Sierra, None; H. Quiroz-Mercado, None; D. Ochoa-Contreras, None; V. Morales-Canton, None.
  • Footnotes
    Support  APEC
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 45. doi:
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      D. Moreno-Paramo, A. Perez-Montesinos, R. Velez-Montoya, M. Martinez-Castellanos, G. Garcia-Aguirre, J. Dalma-Weiszhausz, J. Jimenez-Sierra, H. Quiroz-Mercado, D. Ochoa-Contreras, V. Morales-Canton; Complications After Intravitreal Bevacizumab (Avastin): Analysis of 5132 Injections. Invest. Ophthalmol. Vis. Sci. 2009;50(13):45.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To assess the ocular and systemic complications after intravitreal injection of 2.5mg of Bevacizumab (Avastin).

Methods: : We retrospectively reviewed 5132 cases of intravitreal injections of Bevacizumab (Avastin), 2.5 mg/0.1 ml within a 3 year period in the Retina Service of Asociación para Evitar la Ceguera en Mexico.

Results: : Six eyes (0.11%) with proliferative diabetic retinopathy developed tractional retinal detachment. Seven eyes (0.13%) developed infectious endophtalmitis; one eye presented a rhegmatogenuos retinal detachment (0.01%), 3 vitreous hemorrhage (0.05%) and leakage of vitreous in 3 patients (0.05%).

Conclusions: : Intravitreal injection of bevacizumab seems to be a low risk procedure with a minimal rate of ocular complications.

Keywords: retina • retinal neovascularization • neovascularization 
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