April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Optimizing Visual Outcomes After Penetrating Keratoplasty (PK)
Author Affiliations & Notes
  • J. B. Ciralsky
    Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
  • R. Pineda
    Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
  • K. A. Colby
    Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
  • Footnotes
    Commercial Relationships  J.B. Ciralsky, None; R. Pineda, None; K.A. Colby, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 602. doi:
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    • Get Citation

      J. B. Ciralsky, R. Pineda, K. A. Colby; Optimizing Visual Outcomes After Penetrating Keratoplasty (PK). Invest. Ophthalmol. Vis. Sci. 2009;50(13):602.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To establish optimal graft oversize for a new corneal trephine system.

Methods: : Retrospective review of eighty-five PK’s performed by two experienced corneal surgeons at Massachusetts Eye and Ear Infirmary (MEEI) between January 1, 2005 and February 1, 2007. Three different operative combinations were examined: Group A (28 eyes, old trephine, 0.25mm oversize), Group B (25 eyes, new trephine, 0.25mm oversize) and Group C (32 eye, new trephine, 0.5mm oversize). Post-operative refraction, topography and survival of grafts were compared.

Results: : Demographics and indications were similar in all groups. Mean post-operative astigmatism was higher (5.5 vs. 4.2 diopters (D)) in Group B vs. Group A (p<0.04). Corneal power was flatter for Groups A (38.7 D) and B (37.9) vs. Group C (42.8 D) (p<0.02 and p<0.01). Survival rates were similar for all groups (85.71% Group A, 88.0% Group B, 80.6% Group C) (p>0.05 for all).

Conclusions: : An increase in graft oversize hastened visual recovery following the use of a new trephine system. Surgeons may need to adjust graft parameters when new instrumentation is introduced.

Keywords: cornea: clinical science • transplantation 
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