April 2009
Volume 50, Issue 13
ARVO Annual Meeting Abstract  |   April 2009
Morphological and Functional Analysis of Patients With Central Serous Chorioretinopathy
Author Affiliations & Notes
  • C. M. Eandi
    Eye Clinic, University of Torino, Torino, Italy
  • C. Alovisi
    Eye Clinic, University of Torino, Torino, Italy
  • P. Choleva
    Eye Clinic, University of Torino, Torino, Italy
  • D. Giacomello
    Eye Clinic, University of Torino, Torino, Italy
  • F. M. Grignolo
    Eye Clinic, University of Torino, Torino, Italy
  • Footnotes
    Commercial Relationships  C.M. Eandi, None; C. Alovisi, None; P. Choleva, None; D. Giacomello, None; F.M. Grignolo, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 767. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      C. M. Eandi, C. Alovisi, P. Choleva, D. Giacomello, F. M. Grignolo; Morphological and Functional Analysis of Patients With Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2009;50(13):767.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose: : To investigate the retinal thickness and the retinal sensitivity of retinal areas that showed variations in fundus autofluorescence (FAF) in patients with acute and chronic central serous chorioretinopathy (CSC).

Methods: : In this prospective study eyes with acute and chronic CSC were analysed with optical coherence tomography (OCT Stratus Zeiss, Germany), FAF detected with confocal scanning laser ophthalmoscope (HRA Heidelberg, Germany), and microperimetry (MP1, Nidek Co, Japan) in order to measure the retinal thickness, and the retinal sensitivity of the areas corresponding to altered FAF. All patients were further studied with fluorescein and indocyanine green (ICG) angiography.

Results: : Ten consecutive patients with CSC were enrolled. Mean visual acuity was 20/63. The hypoautofluorescent areas corresponding to the retinal pigment epithelium (RPE) atrophy showed decreased retinal sensitivity, while adiacent areas of increased FAF could be associated both to normal or decreased retinal sensitivity. A decreased retinal thickness in correspondence to hypoautofluorescent areas correlates with the absence of the photoreceptor hypereflective line.

Conclusions: : Microperimetry data significantly correlated with FAF and OCT changes in patients with CSC. FAF, reflecting the functional status of the RPE, provides information on the impact of these lesions, which is confirmed by the retinal sensitivity data and the OCT. These tests provide an important correlation between the functional impact and the morphological aspect in these patients. A larger series may be helpful to assess the value of these diagnostic techniques in monitoring and predicting CSC evolution.

Keywords: choroid • retinal pigment epithelium • retina 

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.