April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
The Clinical Correlation Between Systemic Medical Risk Factors and the Development of Diabetic Retinopathy
Author Affiliations & Notes
  • A. Agarwal
    Ophthalmology,
    Vanderbilt University, Nashville, Tennessee
  • V. Nguyen
    Ophthalmology, Oklahoma University, Oklahoma City, Oklahoma
  • C. Li
    Center for Human Genetics & Research,
    Vanderbilt University, Nashville, Tennessee
  • Footnotes
    Commercial Relationships  A. Agarwal, None; V. Nguyen, None; C. Li, None.
  • Footnotes
    Support  Research to Prevent Blindness
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 1320. doi:https://doi.org/
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    • Get Citation

      A. Agarwal, V. Nguyen, C. Li; The Clinical Correlation Between Systemic Medical Risk Factors and the Development of Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1320. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To analyze medical risk factors involved in the development of diabetic retinopathy (DR) among patients with Type 1 and Type 2 diabetes.

Methods: : Cases were diabetic patients with DR and controls were diabetic patients without DR. A total of 156 Type 1 (63) and Type 2 (93) patients were examined clinically and their extensive medical risk factor data was collected.

Results: : 63 Type 1 constituted 29 cases and 34 controls and 93 Type 2 constituted 38 cases and 55 controls. The average body mass index was higher in Type 2 than Type 1. The average systolic blood pressure was higher in cases than controls for Type 1 (p = 0.426) and Type 2 (p= 0.200). HbA1c was higher in cases than controls in the earlier years for Type 1 and comparable in cases and controls for Type 2. Hypertension was more prevalent in cases than controls for Type 1 (p = 0.00177) and Type 2 (p=0.124). Nephropathy was more prevalent in cases than controls in Type 1 (p= 2.65E-06) and Type 2 (p= 0.128). The prevalence of hyperlipidemia was comparable in all 4 groups. Heart disease was more prevalent in cases than controls for Type 1 (p=0.0247) and comparable in cases and controls for Type 2 .

Keywords: diabetic retinopathy • diabetes • clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology 
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