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A. Agarwal, V. Nguyen, C. Li; The Clinical Correlation Between Systemic Medical Risk Factors and the Development of Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1320. doi: https://doi.org/.
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To analyze medical risk factors involved in the development of diabetic retinopathy (DR) among patients with Type 1 and Type 2 diabetes.
Cases were diabetic patients with DR and controls were diabetic patients without DR. A total of 156 Type 1 (63) and Type 2 (93) patients were examined clinically and their extensive medical risk factor data was collected.
63 Type 1 constituted 29 cases and 34 controls and 93 Type 2 constituted 38 cases and 55 controls. The average body mass index was higher in Type 2 than Type 1. The average systolic blood pressure was higher in cases than controls for Type 1 (p = 0.426) and Type 2 (p= 0.200). HbA1c was higher in cases than controls in the earlier years for Type 1 and comparable in cases and controls for Type 2. Hypertension was more prevalent in cases than controls for Type 1 (p = 0.00177) and Type 2 (p=0.124). Nephropathy was more prevalent in cases than controls in Type 1 (p= 2.65E-06) and Type 2 (p= 0.128). The prevalence of hyperlipidemia was comparable in all 4 groups. Heart disease was more prevalent in cases than controls for Type 1 (p=0.0247) and comparable in cases and controls for Type 2 .
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