April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
Effectiveness and Safety of Topical Nepafenac in Macular Edema Related to Pan-Retinal Photocoagulation
D. O. Rascon-Vargas; J. Fromow-Guerra; G. Cervantes-Coste; A. Perez-Montesinos; E. Torres-Porras; H. Ruíz-García; V. Morales-Canton
Author Affiliations & Notes
  • D. O. Rascon-Vargas
    Retina,
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • J. Fromow-Guerra
    Retina,
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • G. Cervantes-Coste
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • A. Perez-Montesinos
    Retina,
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • E. Torres-Porras
    Retina,
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • H. Ruíz-García
    Retina,
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • V. Morales-Canton
    Retina,
    Asociacion Para Evitar la Ceguea, I.A.P., Mexico City, Mexico
  • Footnotes
    Commercial Relationships  D.O. Rascon-Vargas, None; J. Fromow-Guerra, None; G. Cervantes-Coste, None; A. Perez-Montesinos, None; E. Torres-Porras, None; H. Ruíz-García, None; V. Morales-Canton, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 1351. doi:
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      D. O. Rascon-Vargas, J. Fromow-Guerra, G. Cervantes-Coste, A. Perez-Montesinos, E. Torres-Porras, H. Ruíz-García, V. Morales-Canton; Effectiveness and Safety of Topical Nepafenac in Macular Edema Related to Pan-Retinal Photocoagulation. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1351.

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Abstract

Purpose: : To evaluate effectiveness and safety of topical nepafenac 0.1 % (qid) (Nevanac, Alcon Labs), in modulating macular thickening related to pan-retinal photocoagulation in diabetic patients.

Results: : Nineteen patients were included. There was no statistically significant difference between baseline values of central macular thickness and BCVA between the two groups. Wilcoxon test showed statistically significant increase in macular thickness in both groups, baseline versus two weeks after PRP. No statistically significant differences (U Mann-Whitney test) were found when macular thickness and BCVA were compared between the two groups, two weeks after PRP. 72% of patients experimented transient blurred vision in eye asigned to nepafenac. No other adverse effect was found in both groups.

Clinical Trial: : www.clinicaltrials.gov NCT00801905

Keywords: clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • diabetic retinopathy • edema 
© 2009, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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