Abstract
Purpose: :
To evaluate the potential benefit of a single injection of intravitreal Avastin with cataract extraction. We hypothesized that Avastin administered a month prior to or during surgery would result in better postoperative outcomes in patients with diabetic macular edema.
Methods: :
Retrospective medical record review of twenty-six patients in a large multi-physician vitreoretinal clinic between January of 2006 and April of 2008. Inclusion criteria included eyes with diabetic macular edema, cataract, and intravitreal Avastin injection administered a month prior to or during cataract surgery, pre- and postoperative optical coherence tomography (OCT) and best-corrective visual acuity (BCVA) testing. Exclusion criteria included patients with cystoid macular edema, macular hole, aphakia, pseudophakia, retinal vein occlusion, and macular edema from any other retinal disorder.
Results: :
The mean pre- and postop foveal thickness measurements were 265 and 297. The mean pre- and postop macular volume measurements were 7.41 and 7.90. The mean pre- and postop logmar BCVA was 0.7 and 0.54. Visual outcomes were generally good in this group of patients who had active diabetic retinopathy, with 73% (22 of 30 eyes) showing visual improvement at one month postop.
Keywords: diabetic retinopathy • cataract • retina