April 2009
Volume 50, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2009
From Retinal Microaneurysm to Neovascularization: Similar Depression and Anxiety Level in Diabetic Retinopathy
Author Affiliations & Notes
  • L. Ahmadian
    Family Medicine,
    Bronx Lebanon Hospital Center, New York, New York
  • M. Moradi
    Ophthalmology,
    Bronx Lebanon Hospital Center, New York, New York
  • J. A. Lopez
    Family Medicine,
    Bronx Lebanon Hospital Center, New York, New York
  • M. Mayers
    Ophthalmology,
    Bronx Lebanon Hospital Center, New York, New York
  • D. J. Reich
    Family Medicine,
    Bronx Lebanon Hospital Center, New York, New York
  • Footnotes
    Commercial Relationships  L. Ahmadian, None; M. Moradi, None; J.A. Lopez, None; M. Mayers, None; D.J. Reich, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2009, Vol.50, 1366. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      L. Ahmadian, M. Moradi, J. A. Lopez, M. Mayers, D. J. Reich; From Retinal Microaneurysm to Neovascularization: Similar Depression and Anxiety Level in Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2009;50(13):1366.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Methods: : 97 diabetic patients had baseline evaluations that included the Hospital Depression and Anxiety Scale(HDAS), a detailed ophthalmologic examination, retinal photograph, and measurement of hemoglobin A1C (HbA1c). Diabetic retinopathy(DR) was graded with the International Clinical Classification for DR. Depression and anxiety were measured with the 14-item HDAS for fit to the Rasch model that constructed a hierarchy of the patients, ordered in a linear scale. Differential item functioning (DIF) was performed to examine the confounding effects of demographic variables, severity of retinal vascular changes , and HbA1c level on measurement of depression and anxiety. Regression analysis was performed to determine: 1) correlation between depression or anxiety levels and the presence and severity of retinopathy, 2) whether HbA1C level differed between groups with varying severity of DR.

Results: : The study included 97 diabetics(mean age of 61, SD 1.1)of whom 50 (52%) were women. The mean depression and anxiety raw scores were 7.2(SD .4) and 8.1(SD .4) respectively. Twenty six (27%) patients classified as no-retinopathy and 31(32%) as non-proliferative (NPDR) and 40(41%) with proliferative (PDR) retinopathy. The average HgbA1C level was 8.1. Regression analysis revealed a small correlation between HbA1C level and varying severity of retinopathy (P=.03); the multiple R value was .06. Analysis of variance did not reveal a statistically significant difference in mean HbA1C when comparing diabetic groups (P=.11).The t-test revealed a statistical difference in mean HbA1C between groups with and without DR (P=.03).Rasch analysis showed a better person separation for depression(.85)than anxiety (0.80) with the mean depression and anxiety measures of -.63(logit) and -.66(logit),respectively. After Banforeni adjustment, no item had a significant DIF for gender, education, ethnicity, and DR stage or macular edema. Regression analysis did not show a significant correlation between the depression or anxiety measures and severity of retinopathy (P>.5) or HbA1c level (P=.9).

Keywords: diabetic retinopathy • diabetes • proliferation 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×